Active Recombinant Human IL1R1 Protein

• Cat.No.: IL1R1-214H
• Product Overview: Recombinant Human IL1R1 was expressed in HEK293.

Specification

• Description: This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.
• Source: HEK293
• Species: Human
• Form: 1 x PBS
• Bio-activity: The ED50 is 0.2 - 0.6 µg/ml, corresponding to a specific activity of 1.7 - 5.0 x 10^3 units/mg, determined by the dose dependent inhibition of D10.G4.1 cell proliferation.
• Molecular Mass: 38 kDa
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method.
• Purity: >95%, as determined by Coomassie stained SDS-PAGE.
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer

Gene Information

• Gene Name: IL1R1 interleukin 1 receptor, type I [ Homo sapiens ]
• Official Symbol: IL1R1
• Synonyms: IL1R1; interleukin 1 receptor, type I; IL1R, IL1RA; interleukin-1 receptor type 1; CD121A; D2S1473; IL-1R-1; IL-1RT1; IL-1RT-1; antigen CD121a; interleukin receptor 1; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family member A; interleukin 1 receptor alpha, type I; P80; IL1R; IL1RA; IL-1R-alpha
• Gene ID: 3554
• mRNA Refseq: NM_000877
• Protein Refseq: NP_000868
• MIM: 147810
• UniProt ID: P14778