Recombinant Human IL33 Protein, GST-tagged

• Cat.No.: IL33-5188H
• Product Overview: Human IL33 full-length ORF ( NP_254274.1, 1 a.a. - 270 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Interleukin 33 (IL-33) is a protein that in humans is encoded by the IL33 gene. Interleukin 33 is a member of the IL-1 family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL-4). IL33 is a ligand for ST2 (IL1RL1), an IL-1 family receptor that is highly expressed on Th2 cells, mast cells and group 2 innate lymphocytes. IL-33 is expressed by a wide variety of cell types, including fibroblasts, mast cells, dendritic cells, macrophages, osteoblasts, endothelial cells, and epithelial cells.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 57.2 kDa
• AA Sequence: MKPKMKYSTNKISTAKWKNTASKAL CFKLGKSQQKAKEVCPMYFMKLRSG LMIKKEACYFRRETTKRPSLKTGRK HKRHLVLAACQQQSTVECFAFGISG VQKYTRALHDSSITGISPITEYLAS LSTYNDQSITFALEDESYEIYVEDL KKDEKKDKVLLSYYESQHPSNESGD GVDGKMLMVTLSPTKDFWLHANNKE HSVELHKCEKPLPDQAFFVLHNMHS NCVSFECKTDPGVFIGVKDNHLALI KVDSSENLCTENILFKLSET
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: IL33 interleukin 33 [ Homo sapiens ]
• Official Symbol: IL33
• Synonyms: IL33; interleukin 33; C9orf26, chromosome 9 open reading frame 26 (NF HEV); interleukin-33; DKFZp586H0523; DVS27; DVS27 related protein; IL1F11; interleukin 1 family; member 11; NF HEV; nuclear factor for high endothelial venules; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor from high endothelial venules; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2
• Gene ID: 90865
• mRNA Refseq: NM_001199640
• Protein Refseq: NP_001186569
• MIM: 608678
• UniProt ID: O95760