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Recombinant Human IL4 Protein, GST-tagged

Cat.No. : IL4-5183H
Product Overview : Human IL4 full-length ORF ( NP_000580, 1 a.a. - 153 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 42.46 kDa
AA Sequence : MGLTSQLLPPLFFLLACAGNFVHGH KCDITLQEIIKTLNSLTEQKTLCTE LTVTDIFAASKNTTEKETFCRAATV LRQFYSHHEKDTRCLGATAQQFHRH KQLIRFLKRLDRNLWGLAGLNSCPV KEANQSTLENFLERLKTIMREKYSK CSS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : IL4 interleukin 4 [ Homo sapiens ]
Official Symbol : IL4
Synonyms : IL4; interleukin 4; interleukin-4; B cell growth factor 1; B_cell stimulatory factor 1; BCGF 1; BCGF1; BSF1; IL 4; lymphocyte stimulatory factor 1; MGC79402; binetrakin; pitrakinra; IL-4; BSF-1; BCGF-1;
Gene ID : 3565
mRNA Refseq : NM_000589
Protein Refseq : NP_000580
MIM : 147780
UniProt ID : P05112

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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