Recombinant Human IL4R Protein, GST-tagged
Cat.No. : | IL4R-5179H |
Product Overview : | Human IL4R partial ORF ( NP_000409, 26 a.a. - 135 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 37.84 kDa |
AA Sequence : | MKVLQEPTCVSDYMSISTCEWKMNG PTNCSTELRLLYQLVFLLSEAHTCI PENNGGAGCVCHLLMDDVVSADNYT LDLWAGQQLLWKGSFKPSEHVKPRA PGNLTVHTNV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | IL4R interleukin 4 receptor [ Homo sapiens ] |
Official Symbol : | IL4R |
Synonyms : | IL4R; interleukin 4 receptor; interleukin-4 receptor subunit alpha; CD124; IL-4 receptor subunit alpha; interleukin-4 receptor alpha chain; IL4RA; IL-4RA; |
Gene ID : | 3566 |
mRNA Refseq : | NM_000418 |
Protein Refseq : | NP_000409 |
MIM : | 147781 |
UniProt ID : | P24394 |
Products Types
◆ Recombinant Protein | ||
IL4R-331H | Recombinant Human IL4R Protein, His-tagged | +Inquiry |
IL4R-2321H | Recombinant Human IL4R Protein, His-tagged | +Inquiry |
IL4R-1382C | Acitve Recombinant Cynomolgus IL4R protein(Met1-Arg232), hFc-tagged | +Inquiry |
IL4R-068H | Recombinant Human IL4R Protein, C-His-tagged | +Inquiry |
IL4R-330C | Recombinant Cynomolgus monkey IL4R Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
IL4R-1051RCL | Recombinant Rat IL4R cell lysate | +Inquiry |
IL4R-2719HCL | Recombinant Human IL4R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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