Recombinant Human INVS Protein, GST-tagged

• Cat.No.: INVS-5082H
• Product Overview: Human INVS full-length ORF ( AAH06370, 1 a.a. - 101 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.85 kDa
• AA Sequence: MNKSENLLFAGSSLASQVHAAAVNG DKGALQRLIVGNSALKDKEDQFGRT PLMYCVLADRLDCADALLKAGADVN KTDHSQRTALHLAAQKALRTISTGR I
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: INVS inversin [ Homo sapiens ]
• Official Symbol: INVS
• Synonyms: INVS; inversin; nephronophthisis 2 (infantile) , NPHP2; nephrocystin 2; nephrocystin-2; inversion of embryonic turning; inversion of embryo turning homolog; INV; NPH2; NPHP2; KIAA0573; MGC133080; MGC133081
• Gene ID: 27130
• mRNA Refseq: NM_014425
• Protein Refseq: NP_055240
• MIM: 243305
• UniProt ID: Q9Y283