Recombinant Human ITGA5 Protein

• Cat.No.: ITGA5-4996H
• Product Overview: Human ITGA5 full-length ORF (NP_002196.2) recombinant protein without tag.

Specification

• Description: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 114.5 kDa
• AA Sequence: MGSRTPESPLHAVQLRWGPRRRPPL LPLLLLLLPPPPRVGGFNLDAEAPA VLSGPPGSFFGFSVEFYRPGTDGVS VLVGAPKANTSQPGVLQGGAVYLCP WGASPTQCTPIEFDSKGSRLLESSL SSSEGEEPVEYKSLQWFGATVRAHG SSILACAPLYSWRTEKEPLSDPVGT CYLSTDNFTRILEYAPCRSDFSWAA GQGYCQGGFSAEFTKTGRVVLGGPG SYFWQGQILSATQEQIAESYYPEYL INLVQGQLQTRQASSIYDDSYLGYS VAVGEFSGDDTEDFVAGVPKGNLTY GYVTILNGSDIRSLYNFSGEQMASY FGYAVAATDVNGDGLDDLLVGAPLL MDRTPDGRPQEVGRVYVYLQHPAGI EPTPTLTLTGHDEFGRFGSSLTPLG DLDQDGYNDVAIGAPFGGETQQGVV FVFPGGPGGLGSKPSQVLQPLWAAS HTPDFFGSALRGGRDLDGNGYPDLI VGSFGVDKAVVYRGRPIVSASASLT IFPAMFNPEERSCSLEGNPVACINL SFCLNASGKHVADSIGFTVELQLDW QKQKGGVRRALFLASRQATLTQTLL IQNGAREDCREMKIYLRNESEFRDK LSPIHIALNFSLDPQAPVDSHGLRP ALHYQSKSRIEDKAQILLDCGEDNI CVPDLQLEVFGEQNHVYLGDKNALN LTFHAQNVGEGGAYEAELRVTAPPE AEYSGLVRHPGNFSSLSCDYFAVNQ SRLLVCDLGNPMKAGASLWGGLRFT VPHLRDTKKTIQFDFQILSKNLNNS QSDVVSFRLSVEAQAQVTLNGVSKP EAVLFPVSDWHPRDQPQKEEDLGPA VHHVYELINQGPSSISQGVLELSCP QALEGQQLLYVTRVTGLNCTTNHPI NPKGLELDPEGSLHHQQKREAPSRS SASSGPQILKCPEAECFRLRCELGP LHQQESQSLQLHFRVWAKTFLQREH QPFSLQCEAVYKALKMPYRILPRQL PQKERQVATAVQWTKAEGSYGVPLW IIILAILFGLLLLGLLIYILYKLGF FKRSLPYGTAMEKAQLKPPATSDA
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) [ Homo sapiens ]
• Official Symbol: ITGA5
• Synonyms: ITGA5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); FNRA; integrin alpha-5; CD49e; VLA-5; integrin alpha-F; CD49 antigen-like family member E; fibronectin receptor subunit alpha; fibronectin receptor, alpha subunit; very late activation protein 5, alpha subunit; VLA5A
• Gene ID: 3678
• mRNA Refseq: NM_002205
• Protein Refseq: NP_002196
• MIM: 135620
• UniProt ID: P08648