Recombinant Human JAM3 Protein, Fc-tagged

• Cat.No.: JAM3-496H
• Product Overview: Recombinant human JAM3 (Q9BX67) extracellular domain (Met 1-Asn 241) was fused with the Fc region of human IgG1 at the C-terminus.

Specification

• Source: HEK293
• Species: Human
• Tag: Fc
• Predicted N Terminal: Val 32
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Molecular Mass: The recombinant human JAM3/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 451 amino acids and has a predicted molecular mass of 51 kDa. The reduced monomer migrates as an approximately 60 kDa band in SDS-PAGE under reducing conditions due to glycosylation.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >85 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: JAM3 junctional adhesion molecule 3 [ Homo sapiens ]
• Official Symbol: JAM3
• Synonyms: JAM3; junctional adhesion molecule 3; junctional adhesion molecule C; JAM C; JAMC; JAM-2; JAM-3; JAM-C; FLJ14529
• Gene ID: 83700
• mRNA Refseq: NM_001205329
• Protein Refseq: NP_001192258
• MIM: 606871
• UniProt ID: Q9BX67
• Chromosome Location: 11q25
• Pathway: Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; Hemostasis, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem