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Recombinant Human KCNJ10 protein, GST-tagged

Cat.No. : KCNJ10-2545H
Product Overview : Recombinant Human KCNJ10(C-term-200aa) fused with GST tag was expressed in E. coli.
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Description : This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes.
Source : E. coli
Species : Human
Tag : GST
Form : Protein lyophilized in sterile PBS (58 mM Na2HPO4, 17 mM NaH2PO4, 68 mM NaCl, 100 mM GSH, pH 8.0) and 10% glycerol.
Protein length : C-term-200aa
AA Sequence : ETIRFSQHAVVASHNGKPCLMIRVA NMRKSLLIGCQVTGKLLQTHQTKEG ENIRLNQVNVTFQVDTASDSPFLIL PLTFYHVVDETSPLKDLPLRSGEGD FELVLILSGTVESTSATCQVRTSYL PEEILWGYEFTPAISLSASGKYIAD FSLFDQVVKVASPSGLRDSTVRYGD PEKLKLEESLREQAEKEGSALSVRI SNV
Storage : Aliquot and store at -20 centigrade to -80 centigrade for up to 6 months. Avoid freeze thaw cycles.
Shipping : The product is shipped with ice packs. Upon receipt, store it immediately at -20 centigrade to -80 centigrade.
Gene Name : KCNJ10 potassium inwardly-rectifying channel, subfamily J, member 10 [ Homo sapiens ]
Official Symbol : KCNJ10
Synonyms : KCNJ10; potassium inwardly-rectifying channel, subfamily J, member 10; ATP-sensitive inward rectifier potassium channel 10; Kir1.2; Kir4.1; inward rectifier K+ channel KIR1.2; inward rectifier K(+) channel Kir1.2; ATP-dependent inwardly rectifying potassium channel Kir4.1; potassium channel, inwardly rectifying subfamily J member 10; glial ATP-dependent inwardly rectifying potassium channel KIR4.1; KIR1.2; KIR4.1; SESAME; BIRK-10; KCNJ13-PEN;
Gene ID : 3766
mRNA Refseq : NM_002241
Protein Refseq : NP_002232
MIM : 602208
UniProt ID : P78508
Chromosome Location : 1q23.2
Pathway : Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; G protein gated Potassium channels, organism-specific biosystem; GABA B receptor activation, organism-specific biosystem; GABA receptor activation, organism-specific biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem;
Function : ATP binding; ATP-activated inward rectifier potassium channel activity; identical protein binding; nucleotide binding; potassium channel activity; protein binding; voltage-gated ion channel activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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