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Recombinant Human KRT8 Protein, GST-tagged

Cat.No. : KRT8-4835H
Product Overview : Human KRT8 full-length ORF ( NP_002264.1, 1 a.a. - 483 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 80.1 kDa
AA Sequence : MSIRVTQKSYKVSTSGPRAFSSRSY TSGPGSRISSSSFSRVGSSNFRGGL GGGYGGASGMGGITAVTVNQSLLSP LVLEVDPNIQAVRTQEKEQIKTLNN KFASFIDKVRFLEQQNKMLETKWSL LQQQKTARSNMDNMFESYINNLRRQ LETLGQEKLKLEAELGNMQGLVEDF KNKYEDEINKRTEMENEFVLIKKDV DEAYMNKVELESRLEGLTDEINFLR QLYEEEIRELQSQISDTSVVLSMDN SRSLDMDSIIAEVKAQYEDIANRSR AEAESMYQIKYEELQSLAGKHGDDL RRTKTEISEMNRNISRLQAEIEGLK GQRASLEAAIADAEQRGELAIKDAN AKLSELEAALQRAKQDMARQLREYQ ELMNVKLALDIEIATYRKLLEGEES RLESGMQNMSIHTKTTSGYAGGLSS AYGGLTSPGLSYSLGSSFGSGAGSS SFSRTSSSRAVVVKKIETRDGKLVS ESSDVLPK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : KRT8 keratin 8 [ Homo sapiens ]
Official Symbol : KRT8
Synonyms : KRT8; keratin 8; keratin, type II cytoskeletal 8; CARD2; CK8; CYK8; K2C8; K8; KO; cytokeratin 8; cytokeratin-8; type-II keratin Kb8; CK-8;
Gene ID : 3856
mRNA Refseq : NM_001256282
Protein Refseq : NP_001243211
MIM : 148060
UniProt ID : P05787

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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