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Recombinant Human LGALS9 protein, His & GST-tagged

Cat.No. : LGALS9-558H
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  • Gene Information
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Product overview : Recombinant Human LGALS9 (O00182) aa. (Met1~Thr355) fused with His & GST tag was produced in E. coli cells.
Description : The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
Source : E. coli
Species : Human
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 65.4kDa; Accurate Molecular Mass: 63kDa as determined by SDS-PAGE reducing conditions.
Protein length : Met1~Thr355
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >92%
Characteristic : Isoelectric point is 9.3.
Applications : Cell culture; Activity Assays; In vivo assays.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : 20mM Tris, 150mM NaCl,pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex
Gene Name : LGALS9 galectin 9 [ Homo sapiens (human) ]
Official Symbol : LGALS9
Synonyms : LGALS9; HUAT; LGALS9A; galectin-9; ecalectin; gal-9; lectin, galactoside-binding, soluble, 9; tumor antigen HOM-HD-21; urate transporter/channel protein
Gene ID : 3965
mRNA Refseq : NM_001330163.1
Protein Refseq : NP_001317092.1
UniProt ID : O00182

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any ongoing clinical trials involving LGALS9 protein? 04/12/2023

Yes, there are clinical trials investigating the use of LGALS9-based therapies in cancer treatment, with a focus on immunotherapy approaches.

Is LGALS9 protein being explored for the treatment of infectious diseases? 07/05/2022

There is emerging research on the potential use of LGALS9 in modulating immune responses to infectious diseases, particularly in the context of viral infections.

What are the potential challenges associated with the clinical application of LGALS9 protein? 03/28/2021

Challenges include optimizing the delivery and dosing of LGALS9-based therapies and addressing potential adverse effects on immune homeostasis.

How is LGALS9 protein being studied in the context of transplant immunology? 01/08/2020

LGALS9 is being investigated for its potential to induce immune tolerance and mitigate transplant rejection in preclinical studies.

How does LGALS9 protein contribute to cancer immunotherapy? 12/31/2019

LGALS9 has been found to promote the activation and proliferation of cytotoxic T lymphocytes, which are key players in the immune response against cancer cells.

Customer Reviews (3)

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Reviews
08/04/2019

    It has demonstrated outstanding performance in ELISA, providing reliable and precise results.

    05/05/2019

      It has been invaluable in protein electron microscopy structure analysis, facilitating detailed investigations and yielding valuable insights.

      03/09/2016

        I highly recommend the LGALS9 protein for various experimental applications.

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