Recombinant Human MERTK protein, His-tagged
Cat.No. : | MERTK-149H |
Product Overview : | Recombinant Human MERTK(Met177-Ala499) fused with His tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0. |
Protein length : | Met177-Ala499 |
AA Sequence : | MKINNEEIVSDPIYIEVQGLPHFTK QPESMNVTRNTAFNLTCQAVGPPEP VNIFWVQNSSRVNEQ PEKSPSVLTVPGLTEMAVFSCEAHN DKGLTVSKGVQINIKAIPSPPTEVS IRNSTAHSILISWVP GFDGYSPFRNCSIQVKEADPLSNGS VMIFNTSALPHLYQIKQLQALANYS IGVSCMNEIGWSAVS PWILASTTEGAPSVAPLNVTVFLNE SSDNVDIRWMKPPTKQQDGELVGYR ISHVWQSAGISKELL EEVGQNGSRARISVQVHNATCTVRI AAVTKGGVGPFSDPVKIFIPAHGWV DYAPSSTPAPGNAVD HHHHHH |
Endotoxin : | Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test. |
Purity : | Greater than 95% as determined by reducing SDS-PAGE. |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7 centigradefor 2-7 days.Aliquots of reconstituted samples are stable at < -20 centigradefor 3 months. |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | MERTK c-mer proto-oncogene tyrosine kinase [ Homo sapiens ] |
Official Symbol : | MERTK |
Synonyms : | MERTK; c-mer proto-oncogene tyrosine kinase; tyrosine-protein kinase Mer; mer; RP38; STK kinase; proto-oncogene c-Mer; MER receptor tyrosine kinase; receptor tyrosine kinase MerTK; MER; c-mer; MGC133349; |
Gene ID : | 10461 |
mRNA Refseq : | NM_006343 |
Protein Refseq : | NP_006334 |
MIM : | 604705 |
UniProt ID : | Q12866 |
Chromosome Location : | 2q14.1 |
Pathway : | Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; |
Function : | ATP binding; nucleotide binding; receptor activity; transmembrane receptor protein tyrosine kinase activity; |
Products Types
◆ Recombinant Protein | ||
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MERTK-3218H | Recombinant Human MERTK protein(Glu578-Tyr872) | +Inquiry |
MERTK-950H | Recombinant Human MERTK Protein, MYC/DDK-tagged | +Inquiry |
Mertk-04M | Recombinant Mouse Mertk Protein, hFc tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
MERTK-2888HCL | Recombinant Human MERTK cell lysate | +Inquiry |
MERTK-001HCL | Recombinant Human MERTK cell lysate | +Inquiry |
MERTK-1816MCL | Recombinant Mouse MERTK cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMERTK's involvement in cancer includes promoting tumor cell survival and metastasis. Targeting MERTK is under investigation as a potential therapeutic strategy in cancer treatment.
The Gas6-MERTK signaling axis influences diverse cellular processes, activating downstream effectors such as PI3K/Akt and MAPK pathways. Understanding these signaling events provides insights into MERTK's functional diversity.
MERTK is involved in microglial phagocytosis and synaptic pruning, contributing to neural circuitry development. Dysregulation may affect synaptic connectivity, with implications for neurodevelopmental disorders.
MERTK is involved in immune regulation, influencing inflammatory responses. Dysregulation of MERTK has been implicated in autoimmune disorders, emphasizing its role in maintaining immune homeostasis.
Techniques such as co-immunoprecipitation, flow cytometry, and advanced imaging methods are commonly used to study MERTK, providing insights into ligand interactions, signaling pathways, and cellular functions.
Customer Reviews (3)
Write a reviewFast shipping and excellent service. This product is a lab essential.
Highly recommend for quality and prompt delivery.
Exceptional product, outstanding customer service!
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