Recombinant Human MMP1 protein, T7/His-tagged
Cat.No. : | MMP1-91H |
Product Overview : | Recombinant human MMP1 cDNA (100 – 469 aa, derived from BC013875), fused with T7-His-TEV cleavage site Tag (29aa) at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
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Source : | E. coli |
Species : | Human |
Tag : | T7/His |
Form : | 0.40 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol. |
AA Sequence : | MASMTGGQQMGRGHHHHHHENLYFQ GGEFFVLTEGNPRWEQTHLTYRIEN YTPDLPRADVDHAIEKAFQLWSNVT PLTFTKVSEGQADIMISFVRGDHRD NSPFDGPGGNLAHAFQPGPGIGGDA HFDEDERWTNNFREYNLHRVAAHEL GHSLGLSHSTDIGALMYPSYTFSGD VQLAQDDIDGIQAIYGRSQNPVQPI GPQTPKACDSKLTFDAITTIRGEVM FFKDRFYMRTNPFYPEVELNFISVF WPQLPNGLEAAYEFADRDEVRFFKG NKYWAVQGQNVLHGYPKDIYSSFGF PRTVKHIDAALSEENTGKTYFFVAN KYWRYDEYKRSMDPGYPKMIAHDFP GIGHKVDAVFMKDGFFYFFHGTRQY KFDPKTKRILTLQKANSWFNCRKN |
Purity : | >90% by SDS-PAGE |
Applications : | 1. May be used for in vitro activated MMP1 mediated extracellular matrix protein signal regulation study for various cell differentiation regulation with this protein as either coating matrix protein or soluble factor.2. May be used as MMP1 protein-protein interaction assay.3. As enzymatic substrate for various proteases.4. As potential cancer diagnostic biomarker protein.5. As antigen for specific antibody production. |
Storage : | Keep at -80centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days. |
Gene Name : | MMP1 matrix metallopeptidase 1 (interstitial collagenase) [ Homo sapiens ] |
Official Symbol : | MMP1 |
Synonyms : | MMP1; matrix metallopeptidase 1 (interstitial collagenase); CLG, matrix metalloproteinase 1 (interstitial collagenase); interstitial collagenase; fibroblast collagenase; matrix metalloprotease 1; matrix metalloproteinase 1; CLG; CLGN; |
Gene ID : | 4312 |
mRNA Refseq : | NM_001145938 |
Protein Refseq : | NP_001139410 |
MIM : | 120353 |
UniProt ID : | P03956 |
Chromosome Location : | 11q21-q22 |
Pathway : | Activation of Matrix Metalloproteinases, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Basigin interactions, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem |
Function : | calcium ion binding; metalloendopeptidase activity; peptidase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
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MMP1-799H | Recombinant Human MMP1 Protein, His-tagged | +Inquiry |
MMP1-5412H | Active Recombinant Human MMP1 Protein | +Inquiry |
MMP1-5413H | Recombinant Human MMP1 Protein, GST-tagged | +Inquiry |
MMP1-2535H | Recombinant Human MMP1 protein(111-290 aa), N-MBP & C-His-tagged | +Inquiry |
◆ Native Protein | ||
MMP1-45H | Native Human MMP-1 | +Inquiry |
◆ Lysates | ||
MMP1-2884HCL | Recombinant Human MMP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMMP1 is involved in the remodeling of tissue during wound healing by facilitating the breakdown of damaged extracellular matrix components.
Inhibiting MMP1 activity is being explored as a potential therapeutic strategy to impede cancer progression and metastasis.
MMP1 plays a key role in tissue remodeling by degrading collagen, a major component of the extracellular matrix, which is essential for processes like wound healing.
MMP1 overexpression is associated with various diseases, including rheumatoid arthritis, atherosclerosis, and certain types of cancer.
High MMP1 levels have been correlated with poor prognosis in certain cancer types, making it a potential biomarker for predicting disease outcomes.
Customer Reviews (3)
Write a reviewThe manufacturer can offer technical support and expertise to guide researchers through the experimental process.
The manufacturer can play a vital role in supporting and optimizing the research process.
This guarantees that the protein is reliable, consistent, and suitable for experiments, reducing variability and enhancing the reproducibility of findings.
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