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Recombinant Human MSH2 Protein, His&GST-tagged

Cat.No. : MSH2-621H
Product Overview : Recombinant human MSH2 (NP_000242.1) (Met1-Thr934) was expressed with a C-terminal polyhistidine-tagged GST tag at the N-terminus (his-GST).
  • Specification
  • Gene Information
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Source : Baculovirus-Insect Cells
Species : Human
Tag : His&GST
Predicted N Terminal : Met
Form : Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol, 20 mM GSH, 5% ~ 8% trehalose and mannitol.
Molecular Mass : The recombinant human MSH2 consists 1171 amino acids and predicts a molecular mass of 132.6 kDa.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >90 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) [ Homo sapiens ]
Official Symbol : MSH2
Synonyms : MSH2; mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli); COCA1, mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1); DNA mismatch repair protein Msh2; HNPCC; HNPCC1; hMSH2; FCC1; COCA1; LCFS2;
Gene ID : 4436
mRNA Refseq : NM_000251
Protein Refseq : NP_000242
MIM : 609309
UniProt ID : P43246
Chromosome Location : 2p21
Pathway : BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; Colorectal cancer, organism-specific biosystem; Colorectal cancer, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Mismatch repair, organism-specific biosystem; Mismatch repair, conserved biosystem; Pathways in cancer, organism-specific biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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