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Recombinant Human MT2A Protein, His-GST-tagged

Cat.No. : MT2A-1897H
Product Overview : Recombinant Human MT2A Protein(NP_005944.1)(Asp2~Ala61) is expressed from E. coli with a His and GST Tag at the N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer.
Source : E. coli
Species : Human
Tag : His-GST
Form : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Molecular Mass : 39kDa(Analysis of differences refer to the manual)
Protein length : Asp2~Ala61
AA Sequence : DPNCSCAAGDSCTCAGSCKCKECKC TSCKKSCCSCCPVGCAKCAQGCICK GASDKCSCCA
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Notes : The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Concentration : 200µg/mL
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : MT2A
Official Symbol : MT2A
Synonyms : MT2A; CES1
Gene ID : 4502
mRNA Refseq : NM_005953.3
Protein Refseq : NP_005944.1
MIM : 156360
UniProt ID : P02795

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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