Recombinant Human NCR3 protein, T7/His-tagged
Cat.No. : | NCR3-100H |
Product Overview : | Recombinant human CD337 cDNA (19 – 135 aa) fused with T7-His-TEV cleavage site Tag (29aa) at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Tag : | T7/His |
Form : | 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol. |
AA Sequence : | MASMTGGQQMGRGHHHHHHENLYFQ GGEFLWVSQPPEIRTLEGSSAFLPC SFNASQGRLAIGSVTWFRDEVVPGK EVRNGTPEFRGRLAPLASSRFLHDH QAELHIRDVRGHDASIYVCRVEVLG LGVGTGNGTRLVVEKEHPQLG |
Purity : | >90% by SDS-PAGE |
Applications : | 1. May be used for in vitro non-glycosylated CD337 protein mediated DC or NK cell activations regulation study with this protein as either coating matrix protein or soluble factor.2. May be used for CD337 protein-protein interaction assay.3. As enzymeatic substrate for vasious proteases.4. As antigen for specific antibody production. |
Storage : | Keep at -80centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days. |
Gene Name : | NCR3 natural cytotoxicity triggering receptor 3 [ Homo sapiens ] |
Official Symbol : | NCR3 |
Synonyms : | NCR3; natural cytotoxicity triggering receptor 3; LY117, lymphocyte antigen 117; 1C7; CD337; NKp30; NK-p30; lymphocyte antigen 117; activating NK-A1 receptor; activating natural killer receptor p30; natural killer cell p30-related protein; MALS; LY117; |
Gene ID : | 259197 |
mRNA Refseq : | NM_001145466 |
Protein Refseq : | NP_001138938 |
MIM : | 611550 |
UniProt ID : | O14931 |
Chromosome Location : | 6p21.3 |
Pathway : | Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem; |
Function : | receptor activity; |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe study of NCR3 expression and genetic variations may help tailor treatments for individuals with certain diseases, making it a potential component of personalized medicine.
NCR3 is implicated in the pathogenesis of IBD, and drugs targeting this protein may offer new therapeutic options for patients with IBD.
NCR3 dysfunction has been associated with autoimmune diseases, and understanding its role may lead to new therapies.
Challenges include potential side effects, limited understanding of NCR3 in some diseases, and the need for further clinical validation.
Yes, clinical trials are exploring NCR3-based immunotherapies for various cancers and infectious diseases.
Customer Reviews (3)
Write a reviewChoosing the NCR3 protein from this manufacturer not only provides me with a superior product but also grants me access to unparalleled technical support.
The manufacturer's commitment to customer satisfaction is unmatched.
The manufacturer's commitment to customer satisfaction and their willingness to customize solutions based on specific experimental requirements is commendable.
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