Recombinant Human NPHS2 protein, MYC/DDK-tagged

• Cat.No.: NPHS2-717H
• Product Overview: Recombinant Human NPHS2 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 42 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: NPHS2 NPHS2, podocin [ Homo sapiens ]
• Official Symbol: NPHS2
• Synonyms: PDCN; SRN1; nephrosis 2, idiopathic, steroid-resistant (podocin)
• Gene ID: 7827
• mRNA Refseq: NM_014625
• Protein Refseq: NP_055440
• MIM: 604766
• UniProt ID: Q9NP85
• Chromosome Location: 1q25.2
• Pathway: Nephrin/Neph1 signaling in the kidney podocyte, organism-specific biosystem
• Function: protein binding