Recombinant Human NPPB Protein, GST-tagged

• Cat.No.: NPPB-1298H
• Product Overview: Recombinant Human NPPB Protein (37-71aa) was expressed in E. coli with N-terminal His-SUMO tag.

Specification

• Description: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Tris-based buffer, 50% glycerol.
• Molecular Mass: 31.0 kDa
• AA Sequence: DLETSGLQEQRNHLQGKLSELQVEQTSLEPLQESP
• Purity: Greater than 90% as determined by SDS-PAGE.
• Storage: The shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.

Gene Information

• Gene Name: NPPB natriuretic peptide B [ Homo sapiens (human) ]
• Official Symbol: NPPB
• Synonyms: BNP; NPPB
• Gene ID: 4879
• mRNA Refseq: NM_002521.2
• Protein Refseq: NP_002512.1
• MIM: 600295
• UniProt ID: P16860