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Recombinant Human NTRK1 Protein, DDK/His-tagged

Cat.No. : NTRK1-296H
Product Overview : Recombinant Human NTRK1(Ala33-Gly417), transcript variant 1, fused with DDK/His tag at C-terminal was expressed in HEK293.
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  • Gene Information
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Description : This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Source : HEK293
Species : Human
Tag : DDK/His
Form : 1 x PBS, pH7.4, 10% glycerol
Molecular Mass : 45 kDa
Protein length : Ala33-Gly417
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : NTRK1 neurotrophic tyrosine kinase, receptor, type 1 [ Homo sapiens ]
Official Symbol : NTRK1
Synonyms : NTRK1; neurotrophic tyrosine kinase, receptor, type 1; high affinity nerve growth factor receptor; MTC; TRK; TRKA; gp140trk; Oncogene TRK; tyrosine kinase receptor A; tropomyosin-related kinase A; TRK1-transforming tyrosine kinase protein; TRK1; Trk-A; p140-TrkA; DKFZp781I14186;
Gene ID : 4914
mRNA Refseq : NM_001012331
Protein Refseq : NP_001012331
MIM : 191315
UniProt ID : P04629

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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