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Recombinant Human NTRK3 Protein, DDK-tagged

Cat.No. : NTRK3-754H
Product Overview : Recombinant Human NTRK3(Met-Cys32-Thr299) fused with DDK tag at C-terminal was expressed in Sf9 cells.
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  • Gene Information
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Description : This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
Source : Sf9 cells
Species : Human
Tag : DDK
Form : 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
Molecular Mass : 44.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : NTRK3 neurotrophic tyrosine kinase, receptor, type 3 [ Homo sapiens ]
Official Symbol : NTRK3
Synonyms : NTRK3; neurotrophic tyrosine kinase, receptor, type 3; NT-3 growth factor receptor; TRKC; GP145-TrkC; ETV6-NTRK3 fusion; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; gp145(trkC);
Gene ID : 4916
mRNA Refseq : NM_001007156
Protein Refseq : NP_001007157
MIM : 191316
UniProt ID : Q16288

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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