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Recombinant Human OTX2 protein, T7/His-tagged

Cat.No. : OTX2-193H
Product Overview : Recombinant human OTX2 (2 - 297 aa, Isoform-I, derived from BC032579) fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.
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  • Gene Information
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Source : E. coli
Species : Human
Tag : T7/His
Form : 0.25 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose and DTT.
AA Sequence : MASMTGGQQMGRGHHHHHHENLYFQ GEFMSYLKQPPYAVNGLSLTTSGMD LLHPSVGYPGPWASCPAATPRKQRR ERTTFTRAQLDVLEALFAKTRYPDI FMREEVALKINLPESRVQVWFKNRR AKCRQQQQQQQNGGQNKVRPAKKKT SPAREVSSESGTSGQFTPPSSTSVP TIASSSAPVSIWSPASISPLSDPLS TSSSCMQRSYPMTYTQASGYSQGYA GSTSYFGGMDCGSYLTPMHHQLPGP GATLSPMGTNAVTSHLNQSPASLST QGYGASSLGFNSTTDCLDYKDQTAS WKLNFNADCLDYKDQTSSWKFQVL
Purity : >90% by SDS-PAGE
Storage : Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days.
Gene Name : OTX2 orthodenticle homeobox 2 [ Homo sapiens ]
Official Symbol : OTX2
Synonyms : OTX2; orthodenticle homeobox 2; orthodenticle homolog 2 (Drosophila); homeobox protein OTX2; orthodenticle homolog 2; CPHD6; MCOPS5; MGC45000;
Gene ID : 5015
mRNA Refseq : NM_021728
Protein Refseq : NP_068374
MIM : 600037
UniProt ID : P32243
Chromosome Location : 14q22.3
Function : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; eukaryotic initiation factor 4E binding; protein binding; sequence-specific DNA binding; sequence

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any specific drugs targeting OTX2 currently in development? 09/15/2022

As of my last knowledge update, there were no specific drugs targeting OTX2 in advanced stages of development, but ongoing research might uncover potential drug candidates.

Can OTX2 be a target for gene therapy? 09/29/2020

Yes, gene therapy targeting the OTX2 gene is being investigated as a potential approach for treating disorders related to OTX2 dysfunction.

Can alterations in OTX2 expression be detected through diagnostic tests? 05/13/2017

While not yet widely used in clinical practice, diagnostic tests assessing OTX2 expression levels may become relevant in the future for certain developmental and neurological disorders.

How is OTX2 relevant to cancer research? 12/26/2016

OTX2 has been implicated in certain types of brain tumors, and understanding its role in cancer may provide insights into potential targeted therapies.

Are there any ongoing clinical trials involving OTX2? 12/20/2016

As of my last knowledge update in January 2022, specific clinical trials involving OTX2 were not widely reported. However, ongoing research may have progressed since then.

Customer Reviews (3)

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Reviews
02/18/2023

    The OTX2 protein is of exceptional quality, meeting all my experimental requirements with precision and reliability.

    06/05/2020

      This dedication ensures that I have access to the most advanced and reliable protein in my studies, enhancing the overall quality and impact of my research outcomes.

      06/11/2018

        This exceptional level of support enables me to overcome challenges efficiently and progress smoothly with my research.

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