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Recombinant Human PCM1 protein, His & T7-tagged

Cat.No. : PCM1-8022H
Product Overview : Recombinant Human PCM1 aa. (Pro1913~Ile2024 (Accession # Q15154)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Description : The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 16.0kDa
Protein length : Pro1913~Ile2024 (Accession # Q15154)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 4.3.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Gene Name : PCM1 pericentriolar material 1 [ Homo sapiens (human) ]
Official Symbol : PCM1
Synonyms : PTC4; RET/PCM-1; PCM-1; hPCM-1; pericentriolar material 1, PCM1; pericentriolar material 1 protein
Gene ID : 5108
mRNA Refseq : NM_001315507.1
Protein Refseq : NP_001302436.1
UniProt ID : Q15154

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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