Recombinant Human PLAT protein, His & GST-tagged
Cat.No. : | PLAT-2738H |
Product Overview : | Recombinant Human PLAT aa. (Ile311~Pro562 (Accession # P00750)) fused with N-terminal His & GST tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
Source : | E. coli |
Species : | Human |
Tag : | His & GST |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 59.8kDa |
Protein length : | Ile311~Pro562 (Accession # P00750) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 6.2. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | PLAT plasminogen activator, tissue type [ Homo sapiens (human) ] |
Official Symbol : | PLAT |
Synonyms : | TPA; T-PA; alteplase; plasminogen/activator kringle; reteplase; t-plasminogen activator; tissue-type plasminogen activator |
Gene ID : | 5327 |
mRNA Refseq : | NM_000930.4 |
Protein Refseq : | NP_000921.1 |
UniProt ID : | P00750 |
Products Types
◆ Recombinant Protein | ||
PLAT-5461H | Recombinant Human Plasminogen Activator, Tissue | +Inquiry |
Plat-5463M | Recombinant Mouse Plasminogen Activator, Tissue | +Inquiry |
Plat-4907M | Recombinant Mouse Plat Protein, Myc/DDK-tagged | +Inquiry |
PLAT-8525H | Recombinant Human PLAT protein(Tyr37-Arg310), hFc-tagged | +Inquiry |
PLAT-4154R | Recombinant Rat PLAT Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
PLAT-29690TH | Native Human Human SERPINE1 | +Inquiry |
PLAT-30920TH | Native Human PLAT | +Inquiry |
PLAT-30946TH | Native Human PLAT | +Inquiry |
◆ Lysates | ||
PLAT-1498MCL | Recombinant Mouse PLAT cell lysate | +Inquiry |
PLAT-2833HCL | Recombinant Human PLAT cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0701 | PLAT (Human) Chromogenic Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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