Recombinant Human PLCZ1 protein, His/sumo-tagged
Cat.No. : | PLCZ1-137H |
Product Overview : | Recombinant Human PLCZ1(1-415aa) fused with His/sumotag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His/sumo |
Form : | Tris-based buffer,50% glycerol |
Protein length : | 1-415aa |
AA Sequence : | MEMRWFLSKIQDDFRGGKINLEKTQ RLLEKLDIRCSYIHVKQIFKTSDYP VVLSLENHCSTAQQEVMADNLQATF GESLLSDMLDDFPDTLPSPEALKFK ILVKNKKIGTLKETHERKGSDKRGD NQDKETGVKKLPGVMLFKKKKTRKL KIALALSDLVIYTKAEKFKSFQHSR LYQQFNENNSIGETQARKLSKLRVH EFIFHTRKFITRIYPKATRADSSNF NPQEFWNIGCQMVALNFQTPGLPMD LQNGKFLDNGGSGYILKPHFLRESK SYFNPSNIKEGMPITLTIRLISGIQ LPLTHSSSNKGDSLVIIEVFGVPND QMKQQTRVIKKNAFSPRWNETFTFI IHVPELALIRFVVEGQGLIAGNEFL GQYTLPLLCMNKGYRRIPLFSRMGE SLEPASLFVYVWYVR |
Purity : | >90% ( SDS-PAGE ) |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade. |
Gene Name : | PLCZ1 phospholipase C, zeta 1 [ Homo sapiens ] |
Official Symbol : | PLCZ1 |
Synonyms : | PLCZ1; phospholipase C, zeta 1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; NYD SP27; PLCzeta; PLC-zeta-1; phospholipase C-zeta-1; PI-phospholipase C zeta 1; testis-development protein NYD-SP27; testis-development related NYD-SP27; phosphoinositide phospholipase C-zeta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1; NYD-SP27; MGC149685; |
Gene ID : | 89869 |
mRNA Refseq : | NM_033123 |
Protein Refseq : | NP_149114 |
MIM : | 608075 |
UniProt ID : | Q86YW0 |
Chromosome Location : | 12p13.31 |
Pathway : | Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, organism-specific biosystem; D-myo-inositol-5-phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Inositol phosphate metabolism, PI=> |
Function : | calcium ion binding; hydrolase activity; phosphatidylinositol phospholipase C activity; signal transducer activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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