Recombinant Human PLK1 protein, Flag-tagged, Biotinylated

• Cat.No.: PLK1-73H
• Product Overview: Recombinant Human PLK1 [1-603(end) amino acids of accession number NP_005021.2] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 72 kDa
• Purity: >85% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: PLK1 polo-like kinase 1 [ Homo sapiens ]
• Official Symbol: PLK1
• Synonyms: PLK1; polo-like kinase 1; PLK-1; polo like kinase; PLK; STPK13
• Gene ID: 5347
• mRNA Refseq: NM_005030
• Protein Refseq: NP_005021
• MIM: 602098
• UniProt ID: P53350
• Chromosome Location: 16p
• Pathway: APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem
• Function: ATP binding; anaphase-promoting complex binding; microtubule binding; nucleotide binding; protein binding; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity