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Active Recombinant Human PNMT protein, GST-tagged

Cat.No. : PNMT-197H
Product Overview : Recombinant Human PNMT fused with GST tag at N-terminal was expressed in Insect cells.
  • Specification
  • Gene Information
  • Related Products
Description : Phenylethanolamine N-methyltransferase (PNMT) catalyzes the biosynthesis of adrenaline though methylation of phenylethanolamine. PNMT gene is reported to be involved in various human diseases including early-onset Alzheimer disease, Parkinson's disease, and multiple sclerosis. Expression of PNMT can be stimulated by nicotine.
Source : Insect cells
Species : Human
Tag : GST
Form : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 170 nmol/min/mg
Molecular Mass : 57 kDa
Purity : >95%
Applications : Methyltransferase Assay
Stability : 1 year at -70 centigrade from the date of shipment
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name : PNMT phenylethanolamine N-methyltransferase [ Homo sapiens ]
Official Symbol : PNMT
Synonyms : PNMT; phenylethanolamine N-methyltransferase; PENT; phenylethanolamine N-methylase; noradrenaline N-methyltransferase; PNMTase; MGC34570;
Gene ID : 5409
mRNA Refseq : NM_002686
Protein Refseq : NP_002677
MIM : 171190
UniProt ID : P11086
Chromosome Location : 17q
Pathway : Amine-derived hormones, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Catecholamine biosynthesis, organism-specific biosystem; Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline, organism-specific biosystem;
Function : methyltransferase activity; phenylethanolamine N-methyltransferase activity; transferase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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