Recombinant Human POU5F1 protein, His-tagged
Cat.No. : | POU5F1-321H |
Product Overview : | Recombinant Human POU5F1(1-265aa) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
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Description : | POu domain, class 5, transcription factor 1, also known as OCT4, binds to the octamer motif (5'-ATTTGCAT-3'). This protein forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, uTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
Molecular Mass : | 32.2 kDa (285aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MHFYRLFLGA TRRFLNPEWK GEIDNWCVYV LTSLLPFKIQ SQDIKALQKE LEQFAKLLKQ KRITLGYTQADVGLTLGVLF GKVFSQTTIC RFEALQLSFK NMCKLRPLLQ KWVEEADNNE NLQEICKAET LVQARKRKRT SIENRVRGNL ENLFLQCPKPTLQQISHIAQ QLGLEKDVVR VWFCNRRQKG KRSSSDYAQR EDFEAAGSPF SGGPVSFPLA PGPHFGTPGY GSPHFTALYS SVPFPEGEAFPPVSVTTLGS PMHSN |
Purity : | > 85% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | POU5F1 POU class 5 homeobox 1 [ Homo sapiens ] |
Official Symbol : | POU5F1 |
Synonyms : | POU5F1; POU class 5 homeobox 1; OTF3, POU domain class 5, transcription factor 1; POU domain, class 5, transcription factor 1; MGC22487; OCT3; Oct4; octamer-binding protein 3; octamer-binding protein 4; POU domain transcription factor OCT4; octamer-binding transcription factor 3; octamer-binding transcription factor-3; POU-type homeodomain-containing DNA-binding protein; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; |
Gene ID : | 5460 |
mRNA Refseq : | NM_203289 |
Protein Refseq : | NP_976034 |
MIM : | 164177 |
UniProt ID : | Q01860 |
Chromosome Location : | 6p21.33 |
Pathway : | HIF-2-alpha transcription factor network, organism-specific biosystem; Wnt Signaling Pathway and Pluripotency, organism-specific biosystem; |
Function : | DNA binding; miRNA binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding; ubiquitin protein ligase binding; |
Products Types
◆ Recombinant Protein | ||
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POU5F1-3628H | Recombinant Human POU Class 5 Homeobox 1 | +Inquiry |
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POU5F1-1740H | Recombinant Human POU5F1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
POU5F1-2999HCL | Recombinant Human POU5F1 293 Cell Lysate | +Inquiry |
POU5F1-3000HCL | Recombinant Human POU5F1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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