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Recombinant Human PRKAB2 protein, His/MBP-tagged

Cat.No. : PRKAB2-368H
Product Overview : Recombinant Human PRKAB2(117-225 aa) fused with His/MBP tag was expressed in E. coli.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Source : E. coli
Species : Human
Tag : His/MBP
Form : Liquid in PBS
Protein length : 117-225 aa
Purity : SDS-PAGE >90%
Applications : WB Positive Control
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit [ Homo sapiens ]
Official Symbol : PRKAB2
Synonyms : PRKAB2; protein kinase, AMP-activated, beta 2 non-catalytic subunit; 5-AMP-activated protein kinase subunit beta-2; AMPK beta 2; AMPK beta-2 chain; AMPK subunit beta-2; 5-AMP-activated protein kinase, beta-2 subunit; MGC61468;
Gene ID : 5565
mRNA Refseq : NM_005399
Protein Refseq : NP_005390
MIM : 602741
UniProt ID : O43741

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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