|Product Overview:||Recombinant Human PROC(Ala43-Pro461) fused with His tag at C-terminal was expressed in CHO. The isolated protein was activated by thrombin/thrombomodulin complex and further purified.|
|Predicted N Terminal:||Ala43 (light chain) & Leu212 (heavy chain)|
|Form:||Supplied as a 0.2 μm filtered solution in Tris, NaCl and CaCl2.|
|Bio-activity:||Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >275 pmol/min/µg.|
|Molecular Mass:||Predicted Molecular Mass: 19 (light chain), 29 (heavy chain) kDa;
SDS-PAGE: 22-25 kDa and 40-50 kDa, reducing conditions.
|Endotoxin:||<1.0 EU per 1 μg of the protein by the LAL method.|
|Purity:||>95%, by SDS-PAGE under reducing conditions and visualized by silver stain|
|Storage:||Avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
3 months, -20 to -70 centigrade under sterile conditions after opening.
|Gene Name:||PROC protein C (inactivator of coagulation factors Va and VIIIa) [ Homo sapiens ]|
|Synonyms:||PROC; protein C (inactivator of coagulation factors Va and VIIIa); vitamin K-dependent protein C; autoprothrombin IIA; anticoagulant protein C; blood coagulation factor XIV; PC; APC; PROC1; THPH3; THPH4;|
|Pathway:||Cell surface interactions at the vascular wall, organism-specific biosystem; Common Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Gamma-carboxylation of protein precursors, organism-specific biosystem;|
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