Recombinant Human PROM1 protein, His-tagged
Cat.No. : | PROM1-7072H |
Product Overview : | Recombinant Human PROM1 aa. (Ile171~Asp431) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 28kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Ile171~Asp431 |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >98% |
Characteristic : | The isoelectric point is 6.8. |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200ug/mL |
Storage buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex |
Gene Name : | PROM1 prominin 1 [ Homo sapiens (human) ] |
Official Symbol : | PROM1 |
Synonyms : | PROM1; prominin 1; RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061; prominin-1; antigen AC133; hProminin; hematopoietic stem cell antigen; prominin-like protein 1 |
Gene ID : | 8842 |
mRNA Refseq : | NM_001145847.1 |
Protein Refseq : | NP_001139319.1 |
UniProt ID : | O43490 |
Products Types
◆ Recombinant Protein | ||
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Prom1-120R | Recombinant Rat Prom1 protein(Asn171-Tyr424), mFc-tagged | +Inquiry |
Prom1-5140M | Recombinant Mouse Prom1 Protein, Myc/DDK-tagged | +Inquiry |
PROM1-412H | Recombinant Human PROM1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
PROM1-3437R | Recombinant Rhesus Macaque PROM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PROM1-981RCL | Recombinant Rat PROM1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, PROM1's role is widely studied in various cancers, including brain, breast, colon, and pancreatic cancers.
Various laboratory techniques, such as flow cytometry, immunohistochemistry, and molecular biology assays, are employed to study PROM1 expression and function.
No, PROM1 is also associated with certain eye disorders and is being researched for potential applications in retinal diseases.
Research suggests that it could be a target for treatments aimed at eliminating cancer stem cells and potentially preventing cancer relapse.
The potential impact on normal stem cells and unintended consequences on healthy tissues are areas of concern when targeting PROM1 for therapies.
Customer Reviews (3)
Write a reviewThey can offer detailed characterization data, including purity, stability, and functional assessments, to support researchers' confidence in using the protein in their trials.
Manufacturers can support researchers in developing assays to measure PROM1 protein levels or activity specific to their clinical trial settings.
This may involve guidance in selecting appropriate detection methods, providing assay components, or optimizing protocols for optimal performance and sensitivity.
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