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Recombinant Human PROM1 protein, His-tagged

Cat.No. : PROM1-7072H
Product Overview : Recombinant Human PROM1 aa. (Ile171~Asp431) fused with N-terminal His tag was produced in E. coli cells.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Human
Tag : His
Form : Freeze-dried powder
Molecular Mass : 28kDa as determined by SDS-PAGE reducing conditions.
Protein length : Ile171~Asp431
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >98%
Characteristic : The isoelectric point is 6.8.
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Concentration : 200ug/mL
Storage buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex
Gene Name : PROM1 prominin 1 [ Homo sapiens (human) ]
Official Symbol : PROM1
Synonyms : PROM1; prominin 1; RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061; prominin-1; antigen AC133; hProminin; hematopoietic stem cell antigen; prominin-like protein 1
Gene ID : 8842
mRNA Refseq : NM_001145847.1
Protein Refseq : NP_001139319.1
UniProt ID : O43490

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there specific diseases where PROM1 protein is extensively studied? 01/25/2022

Yes, PROM1's role is widely studied in various cancers, including brain, breast, colon, and pancreatic cancers.

What methods are used to study PROM1 protein in clinical settings? 10/24/2021

Various laboratory techniques, such as flow cytometry, immunohistochemistry, and molecular biology assays, are employed to study PROM1 expression and function.

Is PROM1 exclusively related to cancer and regenerative medicine? 01/05/2019

No, PROM1 is also associated with certain eye disorders and is being researched for potential applications in retinal diseases.

Can PROM1 be a potential target for therapeutic interventions? 08/10/2016

Research suggests that it could be a target for treatments aimed at eliminating cancer stem cells and potentially preventing cancer relapse.

Are there any side effects associated with targeting PROM1 in therapies? 03/06/2016

The potential impact on normal stem cells and unintended consequences on healthy tissues are areas of concern when targeting PROM1 for therapies.

Customer Reviews (3)

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Reviews
05/01/2021

    They can offer detailed characterization data, including purity, stability, and functional assessments, to support researchers' confidence in using the protein in their trials.

    10/01/2017

      Manufacturers can support researchers in developing assays to measure PROM1 protein levels or activity specific to their clinical trial settings.

      12/14/2016

        This may involve guidance in selecting appropriate detection methods, providing assay components, or optimizing protocols for optimal performance and sensitivity.

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