Active Recombinant Human PSG6 protein, His-tagged
Cat.No. : | PSG6-201H |
Product Overview : | Recombinant Human PSG6(Gln35-His424) fused with His tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
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Description : | Pregnancy-specific glycoprotein 6 (PSG-6), also known as PSG10 and PSGGB is a secreted glycoprotein of the PSG family within the CEA (carcinoembryonic antigen) superfamily. Mature human PSG-6 is a 401 amino acid (aa) protein that consists of four tandem immunoglobulin-like domains followed by a 30 aa C-terminal tail. The N-terminal Ig-like domain contains an Arg-Gly-Asp (RGD) sequence which is a consensus integrin-binding motif found in many adhesion proteins. Alternative splicing generates an additional isoform with a substitution in the C-terminal tail. PSG-6 is predominantly expressed in placenta and more weakly in granulocytes. It induces monocyte production of the cytokines IL-6, IL-10, and TGF-beta 1. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | No results obtained. Gln35 inferred from enzymatic pyroglutamate treatment revealing Val36 |
Form : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Bio-activity : | Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.9-4.5 μg/mL. |
Molecular Mass : | Predicted Molecular Mass: 45 kDa SDS-PAGE: 62-73 kDa, reducing conditions |
Endotoxin : | <0.1 EU per 1 μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | Reconstitute at 500 μg/mL in PBS. |
Gene Name : | PSG6 pregnancy specific beta-1-glycoprotein 6 [ Homo sapiens ] |
Official Symbol : | PSG6 |
Synonyms : | PSG6; pregnancy specific beta-1-glycoprotein 6; pregnancy-specific beta-1-glycoprotein 6; PS-beta-G-6; PS-beta-G-10; PS-beta-G-12; pregnancy-specific beta-1-glycoprotein 10; pregnancy-specific beta-1-glycoprotein 12; PSG10; PSBG-6; PSBG-10; PSBG-12; |
Gene ID : | 5675 |
mRNA Refseq : | NM_001031850 |
Protein Refseq : | NP_001027020 |
MIM : | 176395 |
UniProt ID : | Q00889 |
Products Types
◆ Recombinant Protein | ||
PSG6-7367H | Recombinant Human PSG6, His tagged | +Inquiry |
PSG6-182H | Recombinant Human PSG6, His-tagged | +Inquiry |
PSG6-0254H | Recombinant Human PSG6 protein, His-tagged | +Inquiry |
◆ Lysates | ||
PSG6-406HCL | Recombinant Human PSG6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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