Recombinant Human PSMD10 protein, His & T7-tagged

• Cat.No.: PSMD10-1502H
• Product Overview: Recombinant Human PSMD10 aa. (Met1~Gly226 (Accession # O75832)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.2kDa
• Protein length: Met1~Gly226 (Accession # O75832)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 6.2

Gene Information

• Gene Name: PSMD10 proteasome 26S subunit, non-ATPase 10 [ Homo sapiens (human) ]
• Official Symbol: PSMD10
• Synonyms: PSMD10; proteasome 26S subunit, non-ATPase 10; p28; p28(GANK); dJ889N15.2; 26S proteasome non-ATPase regulatory subunit 10; 26S proteasome regulatory subunit p28; ankyrin repeat protein; gankyrin; hepatocellular carcinoma-associated protein p28-II; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
• Gene ID: 5716
• mRNA Refseq: NM_002814.3
• Protein Refseq: NP_002805.1
• UniProt ID: O75832