Active Recombinant Human RSPO1 protein
| Cat.No. : | RSPO1-8392H |
| Product Overview : | Recombinant Human RSPO1 was expressed in CHO. |
- Specification
- Gene Information
- Related Products
| Description : | R-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt modulators. Currently, the family consists of four structurally related secreted ligands (Rspo 1-4), all containing the furin-like and thrombospondin structural domains. Rspo-1 is expressed in certain areas of the developing central nervous system, as well as in the adrenal glands, ovary, testis, thyroid, and trachea. Rspo can interact with the Frizzled/LRP6 receptor complex in a manner that stimulates the Wnt/beta-catenin signaling pathway. |
| Source : | CHO |
| Species : | Human |
| Bio-activity : | R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED50 is 1.0-3.0 ug/ml. |
| Molecular Mass : | R-Spondin-1 is a 26.7 kDa protein consisting of 243 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS-PAGE analysis under reducing conditions. |
| Protein length : | 243 amino acid |
| AA Sequence : | SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR RRKGQQQQQQ QGTVGPLTSA GPA |
| Purity : | Greater than 95% by SDS-PAGE gel and HPLC analyses. |
| Gene Name : | RSPO1 R-spondin 1 [ Homo sapiens ] |
| Official Symbol : | RSPO1 |
| Synonyms : | RSPO1; R-spondin 1; R spondin homolog (Xenopus laevis); R-spondin-1; FLJ40906; RSPONDIN; R-spondin homolog; roof plate-specific spondin-1; RSPO; CRISTIN3; RP11-566C13.1; |
| Gene ID : | 284654 |
| mRNA Refseq : | NM_001038633 |
| Protein Refseq : | NP_001033722 |
| MIM : | 609595 |
| UniProt ID : | Q2MKA7 |
| Chromosome Location : | 1p34.2 |
| Pathway : | Wnt signaling network, organism-specific biosystem; |
| Function : | heparin binding; protein binding; receptor binding; |
Products Types
| ◆ Recombinant Protein | ||
| RSPO1-422H | Recombinant Human RSPO1 Protein, His-tagged | +Inquiry |
| Rspo1-8672M | Active Recombinant Mouse Rspo1 protein(Met1-Gln265), His-tagged | +Inquiry |
| RSPO1-132H | Active Recombinant Human RSPO1 Protein (Ser21-Ala263), N-His-SUMO tagged, Animal-free, Carrier-free | +Inquiry |
| RSPO1-421H | Recombinant Human RSPO1 Protein, His-tagged | +Inquiry |
| RSPO1-278H | Recombinant Active Human RSPO1 Protein, His-tagged(C-ter) | +Inquiry |
| ◆ Lysates | ||
| RSPO1-001MCL | Recombinant Mouse RSPO1 cell lysate | +Inquiry |
| RSPO1-001HCL | Recombinant Human RSPO1 cell lysate | +Inquiry |
| RSPO1-1918HCL | Recombinant Human RSPO1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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