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Recombinant Human S100B protein

Cat.No. : S100B-34H
Product Overview : Recombinant Human S100B was expressed in E.coli and purified by using conventional chromatography techniques.
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Description : S100B also known as protein S100-B. S100B is a protein of the S100 protein family. S100 proteins comprise a multigene family of EF-hand calcium binding proteins that engage in multiple functions in response to cellular stress. S100B protein has been implicated in oligodendrocyte progenitor cell (OPC) regeneration in response to demyelinating insult. Also, S100B and other members of S100 proteins are specifically interact with PP5-TPR and inhibited the PP5-Hsp90 interaction.
Source : E. coli
Species : Human
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol
Molecular Mass : 10.7kDa (92aa)
AA Sequence : MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDNDGDGECD FQEFMAFVAM VTTACHEFFEHE
Purity : >95% by SDS - PAGE
Storage : Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1mg/ml (determined by Bradford assay)
Gene Name : S100B S100 calcium binding protein B [ Homo sapiens ]
Official Symbol : S100B
Synonyms : S100B; protein S100-B; S100beta; NEF; S100; S100-B
Gene ID : 6285
mRNA Refseq : NM_006272
Protein Refseq : NP_006263
MIM : 176990
UniProt ID : P04271
Chromosome Location : 21q22.3
Pathway : Activated TLR4 signalling, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 cascade initiated on plasma membrane, organism-specific biosystem;
Function : RAGE receptor binding; S100 beta binding; calcium ion binding; calcium-dependent protein binding; identical protein binding; protein binding; protein homodimerization activity; protein homodimerization activity; tau protein binding; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does S100B help in the diagnosis of traumatic brain injury (TBI)? 01/29/2023

Elevated S100B levels in the blood can indicate TBI, and its measurement can aid in TBI diagnosis and severity assessment.

What conditions can S100B be used to diagnose? 01/11/2023

S100B can be used to diagnose brain injuries, such as traumatic brain injury and stroke.

How is S100B measured in clinical settings? 02/24/2020

S100B levels are typically measured through a blood test.

What precautions should be taken when interpreting S100B results? 02/02/2017

Results should be interpreted in the context of the patient's clinical history and other diagnostic tests.

How is S100B used in the context of neurodegenerative diseases? 02/07/2016

S100B may help in monitoring disease progression and severity in conditions like Alzheimer's disease.

Customer Reviews (3)

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Reviews
03/15/2022

    One major advantage of S100B protein is its ability to contribute to the understanding of diseases related to aberrant cell cycle regulation, including cancer.

    09/29/2019

      The S100B protein demonstrates exceptional quality, making it an ideal candidate to fulfill my experimental requirements.

      10/23/2018

        The manufacturer of S100B protein plays a crucial role in supporting my research efforts.

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