Recombinant Human SENP2 protein
Cat.No. : | SENP2-32H |
Product Overview : | Recombinant Human SENP2(Asp363-Leu589) was expressed in E. coli. |
- Specification
- Gene Information
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Description : | SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. |
Source : | E. coli |
Species : | Human |
Form : | Supplied as a 0.2 μm filtered solution of 50mM HEPES,5% Glycerol, pH 7.4. |
AA Sequence : | DDLLELTEDMEKEISNALGHGPQDE ILSSAFKLRITRGDIQTLKNYHWLN DEVINFYMNLLVERN KKQGYPALHVFSTFFYPKLKSGGYQ AVKRWTKGVNLFEQEIILVPIHRKV HWSLVVIDLRKKCLK YLDSMGQKGHRICEILLQYLQDESK TKRNSDLNLLEWTHHSMKPHEIPQQ LNGSDCGMFTCKYAD YISRDKPITFTQHQMPLFRKKMVWE ILHQQLL |
Endotoxin : | Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test. |
Purity : | Greater than 95% as determined by reducing SDS-PAGE. |
Storage : | Store at < -20 centigrade, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Gene Name : | SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 [ Homo sapiens ] |
Official Symbol : | SENP2 |
Synonyms : | SENP2; SUMO1/sentrin/SMT3 specific peptidase 2; SUMO1/sentrin/SMT3 specific protease 2; sentrin-specific protease 2; AXAM2; DKFZp762A2316; KIAA1331; SMT3IP2; SMT3-specific isopeptidase 2; sentrin/SUMO-specific protease SENP2; |
Gene ID : | 59343 |
mRNA Refseq : | NM_021627 |
Protein Refseq : | NP_067640 |
MIM : | 608261 |
UniProt ID : | Q9HC62 |
Chromosome Location : | 3q28 |
Pathway : | Nuclear pore complex, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem; Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem; |
Function : | SUMO-specific protease activity; cysteine-type peptidase activity; peptidase activity; protein binding; protein domain specific binding; |
Products Types
◆ Recombinant Protein | ||
SENP2-0889H | Recombinant Human SENP2 Protein (D363-L589), Tag Free | +Inquiry |
SENP2-4976R | Recombinant Rat SENP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SENP2-8014M | Recombinant Mouse SENP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SENP2-0890H | Recombinant Human SENP2 Protein (D363-L589), His tagged | +Inquiry |
SENP2-689H | Active Recombinant Human SENP2, His-tagged | +Inquiry |
◆ Lysates | ||
SENP2-583HCL | Recombinant Human SENP2 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (6)
Ask a questionSENP2 recombinant protein is mainly involved in the SUMOylation process in the human body, affecting protein function and cell signal transduction.
If the level of SENP2 recombinant protein is abnormal, treatment may include the use of drugs or other special treatments, depending on the condition and the doctor's recommendation.
Studies have shown that SENP2 recombinant protein may be associated with cardiovascular disease, liver disease, and lung disease.
Pregnant women's SENP2 recombinant protein levels may change due to the needs of fetal growth and development, and regular monitoring is required.
The current treatments for SENP2 recombinant protein mainly include gene therapy, protein replacement therapy, and drug therapy for the SUMOylation process.
The level of SENP2 recombinant protein can be detected by gene sequencing and protein detection methods.
Customer Reviews (3)
Write a reviewThe structure of SENP2 was validated with no abnormal protein folding or inactivation.
The production process of SENP2 products is environmentally friendly, sustainable and in line with the concept of green production.
SENP2 has good solubility and ion exchange capacity, which is convenient for subsequent experimental processing and purification.
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