Recombinant Human TGFBR2 protein, Fc-tagged
Cat.No. : | TGFBR2-229H |
Product Overview : | Recombinant Human TGFBR2, transcript variant 2, fused with Fc tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH7.2 |
Molecular Mass : | 42.6kD |
AA Sequence : | TIPPHVQKSVNNDMIVTDNNGAVKF PQLCKFCDVRFSTCDNQKSCMSNCS ITSICEKPQEVCVAVWRKNDENITL ETVCHDPKLPYHDFILEDAASPKCI MKEKKKPGETFFMCSCSSDECNDNI IFSEEYNTSNPDVDDIEGRMDEPKS CDKTHTCPPCPAPELLGGPSVFLFP PKPKDTLMISRTPEVTCVVVDVSHE DPEVKFNWYVDGVEVHNAKTKPREE QYNSTYRVVSVLTVLHQDWLNGKEY KCKVSNKALPAPIEKTISKAKGQPR EPQVYTLPPSREEMTKNQVSLTCLV KGFYPSDIAVEWESNGQPENNYKTT PPVLDSDGSFFLYSKLTVDKSRWQQ GNVFSCSVMHEALHNHYTQKSLSLS PGK |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | TGFBR2 transforming growth factor, beta receptor II (70/80kDa) [ Homo sapiens ] |
Official Symbol : | TGFBR2 |
Synonyms : | TGFBR2; transforming growth factor, beta receptor II (70/80kDa); MFS2, transforming growth factor, beta receptor II (70 80kD); TGF-beta receptor type-2; tbetaR-II; TGF-beta receptor type II; TGF-beta type II receptor; TGF-beta receptor type IIB; transforming growth factor-beta receptor type II; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; AAT3; FAA3; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII; |
Gene ID : | 7048 |
mRNA Refseq : | NM_003242 |
Protein Refseq : | NP_003233 |
MIM : | 190182 |
UniProt ID : | P37173 |
Products Types
◆ Recombinant Protein | ||
TGFBR2-1291H | Recombinant Human TGFBR2 Protein (L50-D159), Tag Free | +Inquiry |
TGFBR2-4503R | Recombinant Rhesus Macaque TGFBR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TGFBR2-377H | Active Recombinant Human TGFBR2 protein(Met1-Gln166), His-tagged | +Inquiry |
Tgfbr2-6393M | Recombinant Mouse Tgfbr2 Protein, Myc/DDK-tagged | +Inquiry |
TGFBR2-1290H | Recombinant Human TGFBR2 Protein (L50-D159), His tagged | +Inquiry |
◆ Lysates | ||
TGFBR2-1374RCL | Recombinant Rat TGFBR2 cell lysate | +Inquiry |
TGFBR2-2842HCL | Recombinant Human TGFBR2 cell lysate | +Inquiry |
TGFBR2-1291CCL | Recombinant Cynomolgus TGFBR2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket