Recombinant Human TNFSF14 protein, His & S-tagged

• Cat.No.: TNFSF14-7782H
• Product Overview: Recombinant Human TNFSF14 aa. (His62~Val240 (Accession# O43557)) fused with N-terminal His & S tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
• Source: E. coli
• Species: Human
• Tag: His & S
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 25.4kDa
• Protein length: His62~Val240 (Accession# O43557)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.5.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4

Gene Information

• Gene Name: TNFSF14 TNF superfamily member 14 [ Homo sapiens (human) ]
• Official Symbol: TNFSF14
• Synonyms: TNFSF14; TNF superfamily member 14; LTg; CD258; HVEML; LIGHT; tumor necrosis factor ligand superfamily member 14; herpesvirus entry mediator ligand; tumor necrosis factor (ligand) superfamily, member 14; tumor necrosis factor ligand 1D; tumor necrosis factor superfamily member 14
• Gene ID: 8740
• mRNA Refseq: NM_003807.4
• Protein Refseq: NP_003798.2
• UniProt ID: O43557