Recombinant Human TPBG Protein, His-tagged
Cat.No. : | TPBG-656H |
Product Overview : | Recombinant Human TPBG(Ser32~Ser351) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 20mM Tris, 150mM NaCl,pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Molecular Mass : | 38.7kDa |
Identity : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Protein length : | Ser32~Ser351 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 97% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others |
Gene Name : | TPBG trophoblast glycoprotein [ Homo sapiens ] |
Official Symbol : | TPBG |
Synonyms : | TPBG; trophoblast glycoprotein; 5T4; 5T4 AG; 5T4 oncofetal antigen; 5T4 oncotrophoblast glycoprotein; 5T4 oncofetal trophoblast glycoprotein; M6P1; 5T4AG; |
Gene ID : | 7162 |
mRNA Refseq : | NM_001166392 |
Protein Refseq : | NP_001159864 |
MIM : | 190920 |
UniProt ID : | Q13641 |
Products Types
◆ Recombinant Protein | ||
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TPBG-559H | Recombinant Human TPBG Protein, His-tagged | +Inquiry |
TPBG-9528M | Recombinant Mouse TPBG Protein, His (Fc)-Avi-tagged | +Inquiry |
TPBG-5892R | Recombinant Rat TPBG Protein, His (Fc)-Avi-tagged | +Inquiry |
TPBG-1765R | Recombinant Rat TPBG Protein (32-361 aa), His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
TPBG-852HCL | Recombinant Human TPBG 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (7)
Ask a questionElevated TPBG levels can serve as a biomarker and may correlate with poor prognosis in some cancers.
While the post-translational modifications of TPBG are not fully elucidated, they could affect its localization, stability, and interactions with other proteins.
Specific interacting partners of TPBG that significantly influence its function are still under investigation.
TPBG expression is often upregulated in various types of cancer cells.
TPBG might contribute to immune evasion by interacting with immune cells and modulating immune responses.
TPBG plays roles in cell adhesion, migration, and proliferation in normal cells.
Targeting TPBG could provide a therapeutic avenue, particularly in cancers where it is overexpressed, potentially improving immune response and treatment outcomes.
Customer Reviews (3)
Write a reviewReliable and reproducible results.
Worked well for Western blot.
Great for research purposes.
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