Active Recombinant Human TPP1 protein, His-tagged
Cat.No. : | TPP1-926H |
Product Overview : | Recombinant Human TPP1 protein(AAH14863.1)(Met1-Pro563), fused with His tag, was expressed in Insect Cells. |
- Specification
- Gene Information
- Related Products
Source : | Insect Cells |
Species : | Human |
Tag : | His |
Form : | Supplied as sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% glyPlease contact us for any concerns or special requirements.Please refer to the specific buffer information in the hard copy of CoA. |
Bio-activity : | Measured by the cleavage of AlaAlaPheAMC. The specific activity is > 850 pmoles/min/μg. |
Molecular Mass : | The secreted recombinant human TPP1 (pro form) comprises 554 amino acids and has a predicted molecular mass of 60.7 kDa. The apparent molecular mass of rhTPP1 is approximately 60 kDa in SDS-PAGE under reducing conditions. |
Protein Length : | Met1-Pro563 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | TPP1 tripeptidyl peptidase I [ Homo sapiens ] |
Official Symbol : | TPP1 |
Synonyms : | TPP1; tripeptidyl peptidase I; ceroid lipofuscinosis, neuronal 2, late infantile (Jansky Bielschowsky disease) , CLN2; tripeptidyl-peptidase 1; TPP I; tripeptidyl aminopeptidase; growth-inhibiting protein 1; cell growth-inhibiting gene 1 protein; lysosomal pepstatin insensitive protease; CLN2; GIG1; LPIC; TPP-1; MGC21297; |
Gene ID : | 1200 |
mRNA Refseq : | NM_000391 |
Protein Refseq : | NP_000382 |
MIM : | 607998 |
UniProt ID : | O14773 |
Products Types
◆ Recombinant Protein | ||
TPP1-9542M | Recombinant Mouse TPP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TPP1-4234H | Recombinant Human TPP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TPP1-788C | Recombinant Cynomolgus Monkey TPP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TPP1-874M | Recombinant Mouse TPP1 Protein (Met1-Pro562), His-tagged | +Inquiry |
TPP1-5902R | Recombinant Rat TPP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TPP1-449HCL | Recombinant Human TPP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, several PKMYT1 inhibitors are under development and in preclinical and clinical trials for evaluating their efficacy in cancer treatment.
Yes, several clinical trials are investigating the efficacy of PKMYT1 inhibitors in various cancer types.
PKMYT1 regulates the cell cycle by inhibiting the activity of cyclin-dependent kinases (CDKs), particularly CDK1, which is crucial for G2/M phase transition.
Yes, the expression levels of PKMYT1 can be indicative of the responsiveness of cancer cells to specific treatments, making it a potential predictive biomarker.
Selective PKMYT1 inhibitors aim to minimize effects on normal cells, but potential impacts on the cell cycle of non-cancerous cells are still under investigation.
Customer Reviews (3)
Write a reviewThese resources can enhance the efficiency and accuracy of experimental workflows and contribute to successful outcomes.
The manufacturer's support is crucial for researchers using TPP1 protein in trials.
Their collaboration, expertise, and customized solutions contribute to the successful execution of experiments, reliable data generation, and the advancement of scientific knowledge in the field.
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