Recombinant Human WDR77 protein, GST-tagged
Cat.No. : | WDR77-318H |
Product Overview : | Full-length recombinant human WDR77 protein was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene. |
Source : | Insect cell |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol |
Molecular Mass : | 68 kDa |
Purity : | The purity of WDR77 was determined to be >90% by densitometry. |
Applications : | Enzyme Assay; WB |
Stability : | 1 year at -70 centigrade |
Storage : | Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μL |
Gene Name : | WD repeat domain 77 [ Homo sapiens (human) ] |
Official Symbol : | WDR77 |
Synonyms : | p44; MEP50; MEP-50; HKMT1069; Nbla10071; p44/Mep50 |
Gene ID : | 79084 |
mRNA Refseq : | NM_024102 |
Protein Refseq : | NP_077007 |
MIM : | 611734 |
UniProt ID : | Q9BQA1 |
Products Types
◆ Recombinant Protein | ||
WDR77-6232R | Recombinant Rat WDR77 Protein, His (Fc)-Avi-tagged | +Inquiry |
WDR77-1049H | Recombinant Human WDR77 Protein, His-SUMO-tagged | +Inquiry |
WDR77-4438H | Recombinant Human WDR77 Protein, GST-tagged | +Inquiry |
WDR77-5018R | Recombinant Rhesus Macaque WDR77 Protein, His (Fc)-Avi-tagged | +Inquiry |
WDR77-10150M | Recombinant Mouse WDR77 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
WDR77-333HCL | Recombinant Human WDR77 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
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Q&As (7)
Ask a questionWDR77 can influence cancer progression by regulating cell growth and division.
WDR77 dysregulation is particularly significant in hormonal cancers, impacting androgen receptor signaling.
It plays a role in gene expression by participating in the formation of the spliceosome and ribosome assembly.
Targeting WDR77 in therapy could provide new avenues for treating cancers, especially hormone-driven cancers like prostate cancer.
WDR77 interacts with molecular chaperones and is involved in multiple signaling pathways, influencing cell cycle and apoptosis.
WDR77 is involved in various cellular functions, including RNA processing and ribosome biogenesis.
Mutations in WDR77 can disrupt its normal functions, potentially leading to uncontrolled cell proliferation and cancer.
Customer Reviews (3)
Write a reviewCrucial for decision-making. Accurate and efficient protein analysis.
Exceeds research standards. Trusted for accurate data.
Dependable partner in our experiments. Consistently meets expectations.
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