Recombinant Mouse Alk Protein
Cat.No. : | Alk-15M |
Product Overview : | Recombinant Mouse Alk(aa.19-1042) was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | Notum is an evolutionarily conserved 60 kDa secreted deacylase that regulates Wnt activity. It is tethered to the cell surface by binding to Glypican-like sulfated proteoglycans, and it functions as a Glypican-dependent Wnt inhibitor. Notum hydrolyzes the palmitoyl moiety from Wnt-3a, making the Wnt more hydrophilic and unable to bind to the Frizzled-8 receptor. It also induces the release of cell surface GPI-anchored proteins such as Glypican-3, Cadherin-13, and uPAR. Notum regulates head regeneration in planaria, head formation and neural induction in Xenopus, and long range activity of hedgehog proteins in Drosophila. It is up-regulated in some human hepatocellular carcinomas and colorectal cancers. Within amino acids 88-458, mouse Notum shares 92% and 99% aa sequence identity with human and rat Notum, respectively. |
Source : | HEK293 |
Species : | Mouse |
Form : | Each vial contains 50ug purified protein(1mg/ml) in PBS(pH7.4). |
Protein length : | aa.19-1042 |
Purity : | >95% |
Applications : | ELISA, WB, Immunogen |
Storage : | Store at -80 centigrade, Avoid freeze / thaw cycle. |
Gene Name : | Alk anaplastic lymphoma kinase [ Mus musculus ] |
Official Symbol : | Alk |
Synonyms : | ALK; anaplastic lymphoma kinase; ALK tyrosine kinase receptor; Tcrz; CD246; |
Gene ID : | 11682 |
mRNA Refseq : | NM_007439 |
Protein Refseq : | NP_031465 |
UniProt ID : | P97793 |
Products Types
◆ Recombinant Protein | ||
ALK-01H | Active Recombinant Human ALK Protein, GST-tagged | +Inquiry |
ALK-472M | Recombinant Mouse ALK Protein, His (Fc)-Avi-tagged | +Inquiry |
ALK-16M | Recombinant Macaca nemestrina ALK Protein | +Inquiry |
Alk-577M | Recombinant Mouse Alk Protein, MYC/DDK-tagged | +Inquiry |
ALK-02H | Recombinant Human ALK (L1196M G1202R) Protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket