Recombinant Mouse Amica1 Protein, His-tagged
Cat.No. : | Amica1-974M |
Product Overview : | Recombinant mouse Amica1 (NP_001005421.3) (Met1-Leu281) was expressed with a C-terminal polyhistidine tag. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Mouse |
Tag : | His |
Predicted N Terminal : | Leu 23 |
Form : | Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol. |
Molecular Mass : | The recombinant mouse AMICA1 comprises 270 amino acids and has a predicted molecular mass of 30.9 kDa. The apparent molecular mass of the protein is approximately 47.7 kDa in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | Amica1 adhesion molecule, interacts with CXADR antigen 1 [ Mus musculus ] |
Official Symbol : | Amica1 |
Synonyms : | AMICA1; adhesion molecule, interacts with CXADR antigen 1; junctional adhesion molecule-like; mCrea7; adhesion molecule AMICA; dendritic cell-specific protein CREA7; dendritic-cell specific protein Crea7; AMICA; Crea7; Gm638; MGC61025; |
Gene ID : | 270152 |
mRNA Refseq : | NM_001005421 |
Protein Refseq : | NP_001005421 |
MIM : | |
UniProt ID : | |
Pathway : | Adaptive Immune System, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a |
Function : | cell adhesion molecule binding; |
Products Types
◆ Recombinant Protein | ||
AMICA1-11H | Recombinant Human AMICA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AMICA1-142R | Recombinant Rhesus Macaque AMICA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Amica1-973M | Recombinant Mouse Amica1 protein(Met1-Leu281), hFc-tagged | +Inquiry |
Amica1-10519M | Recombinant Mouse Amica1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Jaml-3631M | Recombinant Mouse Jaml Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
AMICA1-2634HCL | Recombinant Human AMICA1 cell lysate | +Inquiry |
AMICA1-001MCL | Recombinant Mouse AMICA1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (10)
Ask a questionActivation of AMICA1 triggers downstream signaling pathways, such as Rho GTPases, PI3K/AKT, or MAPK/ERK, which modulate cytoskeletal rearrangement, cell survival, and gene expression, impacting cellular functions.
AMICA1 contributes to the formation and maintenance of tissue architecture by promoting cell adhesion, regulating cell polarity, and facilitating tissue-specific cellular organization.
AMICA1 exhibits a tissue-specific expression pattern, with higher expression observed in epithelial tissues, neural tissues, and certain organs like the liver and kidney.
Targeting AMICA1 signaling or interaction with specific antibodies or small molecules holds potential as a therapeutic strategy for diseases associated with abnormal cell adhesion or tissue integrity.
AMICA1 interacts with various cell adhesion molecules, such as cadherins, integrins, or selectins, as well as extracellular matrix components like collagen or fibronectin, facilitating cell-cell and cell-matrix interactions.
AMICA1 can undergo post-translational modifications, including phosphorylation, glycosylation, or ubiquitination, which can affect its adhesive properties, intracellular signaling, or protein stability.
During development and tissue regeneration, AMICA1 expression is dynamically regulated, showing distinct spatiotemporal patterns that coincide with tissue remodeling and organogenesis.
AMICA1 plays a crucial role in cell-cell adhesion and cell migration processes, promoting the formation of stable intercellular junctions and regulating cellular movement and tissue morphogenesis.
Dysregulation of AMICA1 expression or function has been implicated in various diseases, including cancer metastasis, epithelial barrier dysfunction, or neurodevelopmental disorders, underscoring its involvement in disease pathogenesis.
Modulation of AMICA1 expression or activity can influence cellular phenotypes, including cell proliferation, differentiation, and cell fate determination, highlighting its role in tissue homeostasis and development.
Customer Reviews (3)
Write a reviewCompatibility with complex biological matrices for translational research.
Enhanced assay sensitivity for detection of subtle protein changes.
Accurate determination of protein function and activity.
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