Recombinant Mouse ARSI Protein
Cat.No. : | ARSI-1984M |
Product Overview : | Recombinant Mouse ARSI full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Arsi arylsulfatase i [ Mus musculus ] |
Official Symbol : | ARSI |
Gene ID : | 545260 |
mRNA Refseq : | NM_001038499.1 |
Protein Refseq : | NP_001033588.1 |
MIM : | |
UniProt ID : | Q32KI9 |
Products Types
◆ Recombinant Protein | ||
ARSI-463R | Recombinant Rat ARSI Protein, His (Fc)-Avi-tagged | +Inquiry |
ARSI-760M | Recombinant Mouse ARSI Protein, His (Fc)-Avi-tagged | +Inquiry |
ARSI-2503H | Recombinant Human ARSI Protein, His (Fc)-Avi-tagged | +Inquiry |
ARSI-962H | Recombinant Human ARSI | +Inquiry |
ARSI-807R | Recombinant Rat ARSI Protein | +Inquiry |
◆ Lysates | ||
ARSI-39HCL | Recombinant Human ARSI lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (10)
Ask a questionAutosomal recessive multiple sulfatase deficiency is a genetic disorder that results from inherited mutations, so it cannot be prevented at present. However, genetic counseling and testing can help identify carrier status in individuals and guide family planning decisions.
Yes, research is ongoing to better understand the underlying mechanisms of autosomal recessive multiple sulfatase deficiency and to develop potential treatments. This includes studying enzyme replacement therapy, gene therapy, and other innovative approaches.
Diagnosis of autosomal recessive multiple sulfatase deficiency is typically confirmed through clinical evaluation, examination of symptoms, and genetic testing to identify ARSI gene mutations.
The ARSI protein acts on various molecules, including glycosaminoglycans (GAGs) such as heparan sulfate, chondroitin sulfate, and dermatan sulfate. It also acts on sulfated steroids like estrone sulfate and dehydroepiandrosterone sulfate.
Symptoms of autosomal recessive multiple sulfatase deficiency can vary but may include developmental delays, intellectual disability, skeletal abnormalities, skin abnormalities, and in severe cases, organ dysfunction.
Autosomal recessive multiple sulfatase deficiency is a rare and severe disorder, and individuals with the condition typically experience significant health challenges. In most cases, affected individuals may have difficulty having children due to their overall health condition and associated complications. However, family planning decisions should be discussed with healthcare professionals based on individual circumstances.
When the ARSI protein is deficient or non-functional, the removal of sulfate groups from molecules is impaired. This leads to the accumulation of sulfated compounds within cells, disrupting their normal function and potentially causing downstream effects on various biological processes.
There is currently no cure for autosomal recessive multiple sulfatase deficiency, and treatment primarily focuses on managing symptoms and providing supportive care. This may include physical therapy, occupational therapy, and medical interventions to address specific symptoms or complications.
Deficiency or non-functioning of the ARSI protein can result in a condition known as autosomal recessive multiple sulfatase deficiency (MSD). This condition leads to the accumulation of sulfated molecules within cells, causing a variety of symptoms throughout the body.
Yes, there are other proteins and enzymes involved in sulfate metabolism. For example, the ARSJ protein (Arylsulfatase J) is another enzyme that plays a role in removing sulfate groups. Additionally, proteins involved in sulfate transport, such as SLC13A1 and SLC26A2, are important for maintaining sulfate balance within cells.
Customer Reviews (3)
Write a reviewWhether I am studying protein-protein interactions, investigating cellular pathways, or examining protein folding dynamics, the ARSI protein consistently delivers exceptional performance and precise outcomes.
The versatility of the ARSI protein is truly remarkable, as it can be employed across a wide range of applications in my research.
The excellent technical support provided by the manufacturer can solve my problem.
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