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Recombinant Mouse Cd40 protein, His & T7-tagged

Cat.No. : Cd40-6717M
Product Overview : Recombinant Mouse Cd40 aa. (Cys26~Arg193 (Accession # P27512)) fused with N-terminal His & T7 tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Source : E. coli
Species : Mouse
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 22.5kDa.
Protein length : Cys26~Arg193 (Accession # P27512)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.1.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Cd40 CD40 antigen [ Mus musculus (house mouse) ]
Official Symbol : Cd40
Synonyms : IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5; AI326936; B-cell surface antigen CD40; CD40L receptor; T-cell differentiation antigen; tumor necrosis factor receptor superfamily member 5
Gene ID : 21939
mRNA Refseq : NM_011611.2
Protein Refseq : NP_035741.2
UniProt ID : P27512

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can CD40-targeted therapies be used in the treatment of infectious diseases? 05/31/2022

CD40 agonists have the potential to enhance immune responses against infectious agents, but their clinical use in this context is an area of ongoing research.

Are there any approved drugs targeting CD40 for clinical use? 05/07/2021

As of my knowledge cutoff date in January 2022, there were no FDA-approved drugs specifically targeting CD40. However, clinical trials were ongoing for CD40-targeted therapies.

Can CD40-targeted therapies be used in combination with other cancer treatments? 04/24/2019

Yes, CD40-targeted therapies are often investigated in combination with other treatments like checkpoint inhibitors or chemotherapy to enhance their effectiveness.

What are the potential side effects of CD40-targeted therapies in cancer treatment? 09/25/2018

Side effects may include flu-like symptoms, cytokine release syndrome, and immune-related adverse events, which can be managed with supportive care and close monitoring.

Are there ongoing clinical trials exploring CD40-targeted therapies for atherosclerosis? 04/25/2017

Research on CD40-targeted therapies for atherosclerosis is still in the experimental stages and not yet in advanced clinical trials.

Customer Reviews (3)

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Reviews
10/28/2021

    Its utilization in this technique has allowed for precise visualization and determination of protein structures with remarkable clarity and resolution.

    08/11/2021

      The reliable and high-quality results obtained using CD40 protein make it an excellent choice for researchers studying protein structures.

      10/07/2018

        CD40 protein has proved to be an invaluable tool in protein electron microscopy structure analysis.

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