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Recombinant Mouse Cd47 protein, Fc-tagged

Cat.No. : CD47-3095M
Product Overview : Recombinant Mouse Cd47(Gln19-Pro158) fused with Fc tag at C-terminal was expressed in HEK293.
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Description : CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
Source : HEK293
Species : Mouse
Tag : Fc
Form : Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Protein length : Gln19-Pro158
AA Sequence : QLLFSNVNSIEFTSCNETVVIPCIV RNVEAQSTEEMFVKWKLNKSYIFIY DGNKNSTTTDQNFTS AKISVSDLINGIASLKMDKRDAMVG NYTCEVTELSREGKTVIELKNRTAF NTDQGSACSYEEEKG GCKLVSWFSPVDDIEGRMDEPKSCD KTHTCPPCPAPELLGGPSVFLFPPK PKDTLMISRTPEVTC VVVDVSHEDPEVKFNWYVDGVEVHN AKTKPREEQYNSTYRVVSVLTVLHQ DWLNGKE
Endotoxin : Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Purity : Greater than 95% as determined by reducing SDS-PAGE.
Quality Control Test : Has a calculated MW of 40.5 kDa. the reducing (R) protein migrates as 50-66 kDa, and the non-reducing (NR) protein migrates as 100-130 kDa in SDS-PAGE.
Storage : Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
Reconstitution : Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Gene Name : Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) [ Mus musculus ]
Official Symbol : Cd47
Synonyms : CD47; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); leukocyte surface antigen CD47; Rh-related antigen; integrin-associated protein; IAP; Itgp; AA407862; AI848868; AW108519; 9130415E20Rik; B430305P08Rik;
Gene ID : 16423
mRNA Refseq : NM_010581
Protein Refseq : NP_034711
UniProt ID : Q61735
Chromosome Location : 16; 16 B5
Pathway : Cell surface interactions at the vascular wall, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Hemostasis, organism-specific biosystem; Signal regulatory protein (SIRP) family interactions, organism-specific biosystem;
Function : protein binding; thrombospondin receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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