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Recombinant Mouse Cdkn2a protein, His & T7-tagged

Cat.No. : Cdkn2a-7705M
Product Overview : Recombinant Mouse Cdkn2a aa. (Ser3~Thr154 (Accession # P51480)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Mouse
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 19.9kDa
Protein length : Ser3~Thr154 (Accession # P51480)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.9.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Cdkn2a cyclin-dependent kinase inhibitor 2A [ Mus musculus (house mouse) ]
Official Symbol : Cdkn2a
Synonyms : Arf; p16; MTS1; Pctr1; p19ARF; p16INK4a; p19; ARF-INK4a; INK4a-ARF; Ink4a/Arf; p16(INK4a); CDK4I; alternative reading frame; cdkn2a; cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein;; mitochondrial smARF; p16-INK4; p16-INK4a; cyclin-dependent kinase inhibitor 2A
Gene ID : 12578
mRNA Refseq : NM_001040654.1
Protein Refseq : NP_001035744.1
UniProt ID : P51480

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Is CDKN2A testing common in cancer diagnostics? 10/14/2022

Yes, CDKN2A testing is often included in genetic screenings for individuals with a family history of cancer to assess their risk.

Can CDKN2A testing be used for early cancer detection? 04/04/2022

Yes, CDKN2A testing is being investigated as a potential tool for early cancer detection, especially in high-risk individuals.

In which types of cancer is CDKN2A most commonly implicated? 07/07/2021

CDKN2A mutations are frequently found in melanoma, pancreatic cancer, and certain types of familial cancers.

How can knowledge of CDKN2A status influence cancer treatment decisions? 03/02/2020

Understanding CDKN2A status can guide treatment choices, as certain therapies may be more or less effective based on the presence or absence of functional CDKN2A.

Are there any known side effects associated with CDKN2A-targeted therapies? 06/13/2018

The field is still evolving, but as with many targeted therapies, potential side effects are being monitored, and their impact is being studied.

Customer Reviews (3)

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Reviews
05/12/2022

    As a researcher utilizing the CDKN2A protein in my trials, I have experienced notable advantages that contribute to the efficiency and success of my research.

    11/29/2019

      The CDKN2A protein offers exceptional quality.

      10/02/2016

        The manufacturer's responsive and knowledgeable support team is always available to answer my queries or provide guidance, ensuring that I can proceed with my research smoothly and without delays.

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