Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Mouse Flt3l protein, His-tagged

Cat.No. : Flt3l-63M
Product Overview : Recombinant mouse FLT3L, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
  • Specification
  • Gene Information
  • Related Products
Description : FLT3L, also known as fms-related tyrosine kinase 3 ligand, stimulates the proliferation of sub-populations of hematopoietic cells that are enriched for stem and progenitor cells. This factor is a transmembrane protein that undergoes proteolytic cleavage to generate a soluble form of the protein.
Source : Insect cell
Species : Mouse
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 19.3kDa (169aa)18-28kDa (SDS–PAGE under reducing conditions.)
AA Sequence : GTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQPLPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQHHHHHH
Endotoxin : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity : >85% by SDS – PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.5mg/ml (determined by Absorbance at 280nm)
Gene Name : Flt3l FMS-like tyrosine kinase 3 ligand [ Mus musculus ]
Official Symbol : Flt3l
Synonyms : Ly72L; Flt3lg; flt3 ligand
Gene ID : 14256
mRNA Refseq : NM_013520
Protein Refseq : NP_038548
MIM :
UniProt ID : P49772
Chromosome Location : 7 29.14 cM; 7 B2-C
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem
Function : cytokine activity; protein homodimerization activity; receptor tyrosine kinase binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
In what ways does FLT3L impact the differentiation of hematopoietic progenitor cells? 02/21/2023

FLT3L promotes the differentiation of hematopoietic progenitor cells into various blood cell lineages, contributing to the diversity of blood cell types.

Are there any side effects associated with FLT3L-based therapies? 10/07/2022

Common side effects may include flu-like symptoms, fatigue, and gastrointestinal disturbances, but the severity varies among individuals.

How does FLT3L influence dendritic cell development and function? 06/13/2022

FLT3L is a crucial factor in the development and maturation of dendritic cells, playing a role in immune response regulation.

How does FLT3L contribute to the maintenance of hematopoietic stem cells in the bone marrow? 06/30/2021

FLT3L supports the maintenance and self-renewal of hematopoietic stem cells in the bone marrow, influencing the overall balance of blood cell production.

Can FLT3L be used as a prognostic marker in leukemia patients? 05/22/2017

Yes, elevated FLT3L levels can serve as a prognostic marker, helping to predict the likelihood of relapse and overall survival in leukemia patients.

Customer Reviews (3)

Write a review
Reviews
01/23/2023

    I am confident in the manufacturer's ability to deliver outstanding technical support.

    04/04/2021

      By incorporating the FLT3L protein into my experiments, I am confident that I am utilizing a product that meets the highest standards of quality and performance.

      08/28/2018

        Its high purity and integrity provide the necessary assurance for consistent and reliable results, enabling me to achieve precise and meaningful outcomes in my research.

        Ask a Question for All Flt3l Products

        Required fields are marked with *

        My Review for All Flt3l Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends