Recombinant Mouse Gpt Protein, His-tagged
Cat.No. : | Gpt-203M |
Product Overview : | Recombinant Mouse Gpt(Arg143~Gln417) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
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Description : | Gpt played an important role in many functions. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 34.0kDa |
Identity : | Reconstitute in PBS or others |
Protein length : | Arg143~Gln417 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others |
Gene Name : | Gpt glutamic pyruvic transaminase, soluble [ Mus musculus ] |
Official Symbol : | Gpt |
Synonyms : | GPT; glutamic pyruvic transaminase, soluble; alanine aminotransferase 1; ALT1; GPT 1; glutamic--alanine transaminase 1; glutamic--pyruvic transaminase 1; glutamate pyruvate transaminase 1; glutamic pyruvic transaminase 1, soluble; ALT; Gpt1; Gpt-1; 1300007J06Rik; 2310022B03Rik; |
Gene ID : | 76282 |
mRNA Refseq : | NM_182805 |
Protein Refseq : | NP_877957 |
UniProt ID : | Q8QZR5 |
Products Types
◆ Recombinant Protein | ||
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GPT-5304H | Recombinant Human GPT Protein, GST-tagged | +Inquiry |
GPT-2236H | Recombinant Human GPT Protein, MYC/DDK-tagged | +Inquiry |
GPT-2330R | Recombinant Rat GPT Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
GPT-26879TH | Native Human GPT | +Inquiry |
GPT-189P | Active Native Porcine GPT protein | +Inquiry |
GPT-5344H | Native Human Glutamic-Pyruvate Transaminase (alanine aminotransferase) | +Inquiry |
◆ Lysates | ||
GPT-721RCL | Recombinant Rat GPT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe GPT gene, encompassing GPT1 and GPT2, is pivotal in glucose and amino acid metabolism. GPT2 is notably linked to tumorigenesis in various cancers, while the involvement of GPT1 in cancer remains uncertain and requires further exploration.
The GPT gene encodes ALT1, a key enzyme in cellular metabolism. ALT1 facilitates the reversible transamination between alanine and 2-oxoglutarate, crucial for glucose and amino acid metabolism. Elevated serum ALT1 levels are commonly used as a biomarker for liver injury caused by drug toxicity, infection, alcohol, and steatosis.
SMS protein alone doesn't impact LSCC patient prognosis, but when combined with GPT, it shows significance. Inconsistency between SMS transcriptional and protein levels may stem from various factors, including the involvement of regulatory elements and different post-transcriptional and post-translational modifications.
Analysis of LSCC tissues and cell lines revealed an inverse relationship between GPT and SMS expressions, confirmed through qRT-PCR and TCGA data. GPT protein, primarily located in the epithelium, was down-regulated in LSCC tissues.
GPT gene expression serves as a marker for cancer-induced metabolic reprogramming in tissues, indicating shifts in energy metabolism and biosynthetic processes.
Customer Reviews (3)
Write a reviewFantastic customer support. They genuinely care about the success of our research.
Top-notch protein quality! It's our go-to for reliable and reproducible results.
Very happy with this lab product!
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