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Recombinant Mouse HLA-DRB1 Protein, His-tagged

Cat.No. : HLA-DRB1-358M
Product Overview : Recombinant Mouse HLA-DRB1(Val27~Ser264) fused with His tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Mouse
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 31.1kDa
Protein length : Val27~Ser264
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Official Symbol : HLA-DRB1
Official Symbol : HLA-DRB1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What role does HLA-DRB1 play in disease susceptibility and progression? 09/05/2022

HLA-DRB1 alleles are linked to susceptibility and progression of various diseases.

What is the significance of HLA-DRB1 polymorphisms in autoimmune diseases? 04/24/2022

Certain HLA-DRB1 alleles are associated with a higher risk of autoimmune diseases.

How does HLA-DRB1 variability impact transplant compatibility? 03/14/2022

Variability in HLA-DRB1 can affect transplant success, with mismatches potentially leading to rejection.

How is HLA-DRB1 expression regulated in immune cells? 01/03/2022

Its expression is tightly controlled, influenced by cytokines and immune signals.

How does HLA-DRB1 contribute to antigen presentation? 10/29/2020

It binds peptides from extracellular proteins, presenting them on the cell surface for T cell recognition.

What is the primary role of HLA-DRB1 in the immune system? 03/11/2019

HLA-DRB1 is crucial for immune responses, presenting peptides to CD4+ T cells.

Are there any therapeutic approaches targeting HLA-DRB1? 02/27/2019

Therapeutic strategies might involve modulating HLA-DRB1 expression or function in autoimmune diseases or transplantation.

Customer Reviews (3)

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Reviews
02/14/2022

    Consistently good quality.

    09/04/2021

      Great product, fast shipping.

      03/30/2020

        Excellent quality, very pure.

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