Recombinant Mouse Icam1 Protein, His-tagged

• Cat.No.: ICAM1-23M
• Product Overview: Recombinant Mouse Icam1(28-485aa) fused with His tag at C-terminal was expressed in Insect cells.

Specification

• Description: ICAM1, also known as intercellular adhesion molecule 1, belongs to the ICAM proteins. The proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
• Source: Insect cells
• Species: Mouse
• Tag: His
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 51.2kDa (466aa) 70-100KDa (SDS-PAGE under reducing conditions.)
• Protein length: 28-485aa
• AA Sequence: QVSIHPREAF LPQGGSVQVN CSSSCKEDLS LGLETQWLKD ELESGPNWKL FELSEIGEDS SPLCFENCGT VQSSASATIT VYSFPESVEL RPLPAWQQVGKDLTLRCHVD GGAPRTQLSA VLLRGEEILS RQPVGGHPKD PKEITFTVLA SRGDHGANFS CRTELDLRPQ GLALFSNVSE ARSLRTFDLP ATIPKLDTPDLLEVGTQQKL FCSLEGLFPA SEARIYLELG GQMPTQESTN SSDSVSATAL VEVTEEFDRT LPLRCVLELA DQILETQRTL TVYNFSAPVL TLSQLEVSEGSQVTVKCEAH SGSKVVLLSG VEPRPPTPQV QFTLNASSED HKRSFFCSAA LEVAGKFLFK NQTLELHVLY GPRLDETDCL GNWTWQEGSQ QTLKCQAWGNPSPKMTCRRK ADGALLPIGV VKSVKQEMNG TYVCHAFSSH GNVTRNVYLT VLYHSQNNVE HHHHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: > 95% by SDS - PAGE.
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: Icam1 intercellular adhesion molecule 1 [ Mus musculus ]
• Official Symbol: Icam1
• Synonyms: ICAM1; intercellular adhesion molecule 1; myD10; CD54; Ly-47; Icam-1; MALA-2; MGC6195
• Gene ID: 15894
• mRNA Refseq: NM_010493
• Protein Refseq: NP_034623
• UniProt ID: P13597