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Recombinant Mouse Il5ra protein, His & T7-tagged

Cat.No. : Il5ra-7064M
Product Overview : Recombinant Mouse Il5ra aa. (Ala41~Lys203 (Accession # P21183)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Mouse
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 22.4kDa
Protein length : Ala41~Lys203 (Accession # P21183)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 7.3.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Il5ra interleukin 5 receptor, alpha [ Mus musculus (house mouse) ]
Official Symbol : Il5ra
Synonyms : Il5ra; interleukin 5 receptor, alpha; Il5r; CD125; CDw125; interleukin-5 receptor subunit alpha; IL-5 receptor alpha chain; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA
Gene ID : 16192
mRNA Refseq : NM_008370.2
Protein Refseq : NP_032396.1
UniProt ID : P21183

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the clinical applications of IL5RA? 10/20/2022

Recombinant IL5RA can be used to treat IL5-related diseases, such as severe asthma and eosinophilic diseases. It can reduce the frequency and severity of asthma attacks by blocking the signaling of interleukin 5.

Can recombinant IL5RA be used to treat other diseases? 06/03/2022

Currently, recombinant IL5RA is mainly used to treat IL5-related diseases, such as severe asthma and eosinophilic diseases. For other diseases, the suitability of IL5RA is subject to further research and clinical trials.

Does the use of IL5RA require blood routine examination? 12/10/2020

During the use of IL5RA, the doctor may ask to check the patient's blood routine regularly to monitor changes in blood counts and related indicators. This helps to evaluate the efficacy of the treatment and the safety of the patient.

Does IL5RA cause dependence? 10/26/2019

There is no clear evidence that long-term use of recombinant IL5RA causes dependence. For patients using IL5RA, it is best to treat and discontinue the drug according to the advice and guidance of their doctor.

What is the use of IL5RA? 10/22/2019

IL5RA is generally administered by subcutaneous injection. The specific use method and dosage should be determined according to the doctor's recommendation and the specific situation of the patient.

What are the side effects of IL5RA? 06/18/2019

Common side effects of recombinant IL5RA include pain at the injection site, redness and swelling at the injection site, cough, and sore throat. A small number of patients may experience allergic reactions or serious adverse reactions, so close monitoring of the patient's condition and signs is required when using.

Customer Reviews (3)

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Reviews
04/05/2021

    Good stability under different temperature and humidity conditions.

    03/27/2021

      In the process of purification, the removal of impurities is good.

      11/13/2020

        Chemical modifications, such as PEGylation or glycosylation, have little effect.

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